494178

1-Bromo-2-ethynylbenzene

95%

• Linear Formula: HC≡CC₆H₄Br
• CAS Number: 766-46-1
• Molecular Weight: 181.03
• MDL number: MFCD01863358
• UNSPSC Code: 12352100
• PubChem Substance ID: 24872882
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: 95%
• refractive index: n20/D 1.595 (lit.)
• bp: 92-93 °C/20 mmHg (lit.)
• density: 1.443 g/mL at 25 °C (lit.)
• functional group: bromo
• SMILES string: Brc1ccccc1C#C
• InChI: 1S/C8H5Br/c1-2-7-5-3-4-6-8(7)9/h1,3-6H
• InChI key: RVDOYUFNRDGYGU-UHFFFAOYSA-N

Description

General description

1-Bromo-2-ethynylbenzene (BEB) is a haloalkyne. It undergoes Sonogashira coupling with methyl 2-iodobenzoate to form bromo tolane derivative.

Application

1-Bromo-2-ethynylbenzene may be used in the synthesis of 1-(2-bromophenyl)-2-(dibenzo[b,d]thiophen-4-yl)ethanone.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point(F): 145.4 °F - closed cup
• Flash Point(C): 63 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves