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Key Documents

419443

Sigma-Aldrich

2-Amino-5-methylbenzoic acid

99%

Synonym(s):

5-Methylanthranilic acid

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About This Item

Linear Formula:
H2NC6H3(CH3)CO2H
CAS Number:
Molecular Weight:
151.16
Beilstein:
1101527
EC Number:
MDL number:
UNSPSC Code:
12352106
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

99%

reaction suitability

reaction type: solution phase peptide synthesis

mp

175 °C (dec.) (lit.)

application(s)

peptide synthesis

SMILES string

Cc1ccc(N)c(c1)C(O)=O

InChI

1S/C8H9NO2/c1-5-2-3-7(9)6(4-5)8(10)11/h2-4H,9H2,1H3,(H,10,11)

InChI key

NBUUUJWWOARGNW-UHFFFAOYSA-N

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General description

2-Amino-5-methylbenzoic acid also known as 5-methylanthranilic acid, is often used in the solution-phase peptide synthesis.

Application

2-Amino-5-methylbenzoic acid can be used to synthesize quinazolinedione.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Synthesis and evaluation of quinazolines as inhibitors of the bacterial cell division protein FtsZ
GM Nepomuceno
ACS Medicinal Chemistry Letters, 6, 308-312 (2015)
João Daniel Santos Fernandes et al.
PloS one, 10(7), e0132369-e0132369 (2015-07-15)
Metabolic diversity is an important factor during microbial adaptation to different environments. Among metabolic processes, amino acid biosynthesis has been demonstrated to be relevant for survival for many microbial pathogens, whereas the association between pathogenesis and amino acid uptake and

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