PHL80473

(-)-Hydroxycitric acid lactone

phyproof^® Reference Substance

• Synonym(s): (+)-Garcinia acid, (−)-Hydroxycitric acid lactone, (2S,3S)-3-Hydroxy-5-oxotetrahydrofuran-2,3-dicarboxylic acid, Garcinia lactone
• Empirical Formula (Hill Notation): C₆H₆O₇
• CAS Number: 27750-13-6
• Molecular Weight: 190.11
• MDL number: MFCD06656311
• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• grade: primary reference standard
• product line: phyproof^® Reference Substance
• Assay: ≥95.0% (HPLC)
• form: solid
• manufacturer/tradename: PhytoLab
• storage temp.: 2-8°C
• SMILES string: OC(=O)[C@H]1OC(=O)C[C@@]1(O)C(O)=O
• InChI: 1S/C6H6O7/c7-2-1-6(12,5(10)11)3(13-2)4(8)9/h3,12H,1H2,(H,8,9)(H,10,11)/t3-,6+/m1/s1
• InChI key: PFHZIWAVXDSFTB-CVYQJGLWSA-N

Description

General description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by Phytolab GmbH & Co. KG

Application

• Analysis of (-)-Hydroxycitric acid lactone in herbal products: A study employed capillary zone electrophoresis for the separation and analysis of (-)-Hydroxycitric acid and its lactone form, demonstrating its application in the quality control of herbal products containing Garcinia atroviridis Griff. This analytical method facilitates the accurate determination of active components in dietary supplements, supporting metabolic and enzyme inhibition studies (Muensritharam et al., 2008).


• Quantitative analysis in Garcinia species: Research developed an improved liquid chromatographic method for the determination of organic acids including (-)-Hydroxycitric acid in various parts of Garcinia plants. This method is vital for metabolic pathway research, offering precise quantification crucial for studies related to weight loss and enzyme inhibition (Jayaprakasha et al., 2003).

Legal Information

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H319
• Precautionary Statements: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Eye Irrit. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable