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Key Documents

SAB5702281

Sigma-Aldrich

Anti-Osteocalcin (BGLAP) Antibody, clone 2T1J7, Rabbit Monoclonal

Synonym(s):

BGLAP,BGP,OC,OCN,osteocalcin

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.46

biological source

rabbit

Quality Level

material

colorless

clone

2T1J7, monoclonal

form

liquid

mol wt

11 kDa

species reactivity

human, rat, rat

concentration

1 mg/mL

technique(s)

western blot: 1:500 - 1:1000

color

colorless

isotype

IgG

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... BGLAP(632)

General description

This gene encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. The encoded protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Read-through transcription exists between this gene and the neighboring upstream gene, PMF1 (polyamine-modulated factor 1), but the encoded protein only shows sequence identity with the upstream gene product.

Immunogen

PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Recombinant protein of Human BGLAP.

Application

WB

Pictograms

Exclamation markEnvironment

Signal Word

Warning

Hazard Statements

Hazard Classifications

Aquatic Chronic 2 - Skin Sens. 1

Storage Class Code

10 - Combustible liquids

WGK

WGK 3


Certificates of Analysis (COA)

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