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L2752

Sigma-Aldrich

Leu-Leu

>98% (TLC), suitable for ligand binding assays

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About This Item

Empirical Formula (Hill Notation):
C12H24N2O3
CAS Number:
3303-31-9
Molecular Weight:
244.33
EC Number:
221-976-6
MDL number:
MFCD00065185
UNSPSC Code:
12352202
PubChem Substance ID:
24896323
NACRES:
NA.26

product name

Leu-Leu,

Assay

>98% (TLC)

form

powder

technique(s)

ligand binding assay: suitable

color

white to off-white

storage temp.

−20°C

SMILES string

CC(C)C[C@H](N)C(=O)N[C@@H](CC(C)C)C(O)=O

InChI

1S/C12H24N2O3/c1-7(2)5-9(13)11(15)14-10(12(16)17)6-8(3)4/h7-10H,5-6,13H2,1-4H3,(H,14,15)(H,16,17)/t9-,10-/m0/s1

InChI key

LCPYQJIKPJDLLB-UWVGGRQHSA-N

Related Categories

Amino Acid Sequence

Leu-Leu

Biochem/physiol Actions

Leucylleucine (Leu-Leu) may be used to study the functionality of dileucine motifs such as the motif responsible for internalization and targeting of vesicular acetylcholine transporter and clathrin adaptors AP-1 and AP-2.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Journal of neuroinflammation, 15(1), 161-161 (2018-05-29)
Microglia-mediated neuroinflammation is recognized to mainly contribute to the pathogenesis of Parkinson's disease (PD). Tetrahydroxystilbene glucoside (TSG) has been proved to be beneficial for health with a great number of pharmacological properties. We examined the effects of TSG against dopamine
S Martinez-Arca et al.
Journal of cell science, 113 ( Pt 10), 1705-1715 (2000-04-19)
The mechanisms by which the insulin-sensitive glucose transporter, GLUT4, is targeted and retained in a storage compartment near to the Golgi complex are poorly understood. Here we report that removal of the carboxyl-terminal acidic Pro(505)AspGluAsnAsp(509) sequence prevents the storage of
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Citicoline or CDP-choline is a drug, made up by a cytidine 5'-diphosphate moiety and choline, which upon adsorption is rapidly hydrolyzed into cytidine 5'-diphosphate and choline, easily bypassing the blood-brain barrier. Once in the brain, these metabolites are used to
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