D3506

Sodium diethyldithiocarbamate trihydrate

• Synonym(s): Cupral, Diethyldithiocarbamic acid sodium salt
• Linear Formula: (C₂H₅)₂NCSSNa · 3H₂O
• CAS Number: 20624-25-3
• Molecular Weight: 225.31
• Beilstein: 3920507
• EC Number: 205-710-6
• MDL number: MFCD00150617
• UNSPSC Code: 12352200
• PubChem Substance ID: 57654092
• NACRES: NA.77

Properties

• vapor density: 5.9 (vs air)
• Quality Level: 200
• Assay: ≥97% (perchloric acid titration)
• form: powder or crystals
• mp: 95-98.5 °C (lit.)
• solubility: water: 1 g/10 mL, slightly hazy
• storage temp.: room temp
• SMILES string: [H]O[H].[H]O[H].[H]O[H].CCN(CC)C(=S)S[Na]
• InChI: 1S/C5H11NS2.Na.3H2O/c1-3-6(4-2)5(7)8;;;;/h3-4H2,1-2H3,(H,7,8);;3*1H2/q;+1;;;/p-1
• InChI key: WWGXHTXOZKVJDN-UHFFFAOYSA-M

Description

Application

Spin trap used in conjunction with Fe²⁺ to detect NO in brain, kidney, liver, and other tissues. Simultaneous direct measurement of NO* and pO₂ has been reported. A copper chelator, it has been used to quantitate copper in biological materials by ESR and is an inhibitor of superoxide dismutase, ascorbate oxidase, and other enzymes.

Biochem/physiol Actions

Inhibits induction of macrophage nitric oxide synthase.

Features and Benefits

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Caution

May form insoluble oxidation products in storage. Sensitivity in colorimetric copper determination not usually affected.

Safety Information

• Pictograms: GHS05,GHS07
• Signal Word: Danger
• Hazard Statements: H302,H315,H318
• Precautionary Statements: P264 - P270 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves