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271748

Sigma-Aldrich

Pyridoxal hydrochloride

99%

Synonym(s):

3-Hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde hydrochloride, PL HCl

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About This Item

Empirical Formula (Hill Notation):
C8H9NO3 · HCl
CAS Number:
Molecular Weight:
203.62
Beilstein:
3656994
EC Number:
MDL number:
UNSPSC Code:
12352205
PubChem Substance ID:
NACRES:
NA.79

biological source

synthetic (Organic)

Quality Level

Assay

99%

form

powder

color

white to off-white

mp

173 °C (dec.) (lit.)

storage temp.

2-8°C

SMILES string

Cl[H].[H]C(=O)c1c(CO)cnc(C)c1O

InChI

1S/C8H9NO3.ClH/c1-5-8(12)7(4-11)6(3-10)2-9-5;/h2,4,10,12H,3H2,1H3;1H

InChI key

FCHXJFJNDJXENQ-UHFFFAOYSA-N

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General description

Pyridoxal, a form of vitamin B6, is a water soluble vitamin. The food sources of vitamin B6 include grains, nuts, fruits, vegetables and meat.

Application

For the labeling of amino acids and their detection in picomolar amounts; Coenzymes and Cofactors, vol. 1: Vitamin B6, Pyridoxal Phosphate
Pyridoxal hydrochloride has been used to test its potential contribution to plant stress tolerance. It has also been used as a supplement in modified M9 minimal medium to culture E. coli BL21(DE3) cells for expression of 15N-labeled ATG101.

Biochem/physiol Actions

Vitamin B6 plays a key role in metabolism of both carbohydrates and amino acids. It is implicated in the synthesis of neurotransmitters like dopamine from L-DOPA, serotonin from 5-HTP, and γaminobutyric acid (GABA) from glutamate. Vitamin B6 plays a major role in maintenance of a healthy nervous system.

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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B Vitamins in the nervous system: Current knowledge of the biochemical modes of action and synergies of thiamine, pyridoxine, and cobalamin
Calderon-Ospina CA, et al.
CNS Neuroscience & Therapeutics (2019)
Hydrosoluble vitamins
Handbook of Clinical Neurology (2014)
The mammalian autophagy initiator complex contains 2 HORMA domain proteins
Michel M, et al.
Autophagy, 11(12), 2300-2308 (2015)
Root metabolic plasticity underlies functional diversity in mycorrhiza-enhanced stress tolerance in tomato
Rivero J, et al.
The New phytologist, 220(4), 1322-1336 (2018)
Vitamin B6 and its role in cell metabolism and physiology
Parra M, et al.
Cells, 7(7), 84-84 (2018)

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