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Sodium perchlorate monohydrate

suitable for HPLC, LiChropur, 99.0-101.0% (T)

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About This Item

Linear Formula:
NaClO4 · H2O
CAS Number:
Molecular Weight:
140.46
MDL number:
UNSPSC Code:
41116105
NACRES:
NB.21
Pricing and availability is not currently available.

Assay

99.0-101.0% (T)

form

solid

manufacturer/tradename

LiChropur

technique(s)

HPLC: suitable

pH

4.5-8.0

solubility

H2O: 5%, clear, colorless

λ

10 % in water

UV absorption

λ: 210 nm Amax: ≤0.1
λ: 220 nm Amax: ≤0.05
λ: 230 nm Amax: ≤0.03
λ: 240 nm Amax: ≤0.02
λ: 500 nm Amax: ≤0.02

SMILES string

O.[Na+].[O-]Cl(=O)(=O)=O

InChI

1S/ClHO4.Na.H2O/c2-1(3,4)5;;/h(H,2,3,4,5);;1H2/q;+1;/p-1

InChI key

IXGNPUSUVRTQGW-UHFFFAOYSA-M

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Application

Sodium perchlorate monohydrate along with acetonitrile may be used as a mobile phase in:
  • Determination of methenamine, methenamine mandelate and methenamine hippurate in pharmaceutical preparations using ion-exchange high-performance liquid chromatography (HPLC).[1]
  • Development and validation of RP-HPLC method for the dissolution and assay of etoricoxib in pharmaceutical dosage forms.[2]
  • Determination of nitrate and nitrite by HPLC in human plasma.[3]

Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

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Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Ox. Sol. 1

Storage Class Code

5.1A - Strongly oxidizing hazardous materials

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Certificates of Analysis (COA)

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Determination of nitrate and nitrite by high-performance liquid chromatography in human plasma
Jedlickova V, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 780(1), 193-197 (2002)
Development and validation of RP-HPLC method for the dissolution and assay of etoricoxib in pharmaceutical dosage forms
Singh B, et al.
International Journal of Pharmaceutical Quality Assurance, 6(01), 1-7 (2015)
Chiravi Pavitrapok et al.
Journal of pharmaceutical and biomedical analysis, 40(5), 1243-1248 (2005-11-22)
An ion-exchange column high-performance liquid chromatography (HPLC) method has been developed for the determination of methenamine in methenamine and methenamine hippurate pharmaceutical preparations. The HPLC method uses a Zorbax SCX-300 column with acetonitrile-0.1M sodium perchlorate monohydrate (pH 5.8) (70:30, v/v)

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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