MABN316

Anti-SLC38A3 Antibody, clone 1A10.2

clone 1A10.2, from mouse

• Synonym(s): Sodium-coupled neutral amino acid transporter 3, N-system amino acid transporter 1, Na(+)-coupled neutral amino acid transporter 3, Solute carrier family 38 member 3, System N amino acid transporter 1
• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Properties

• biological source: mouse
• Quality Level: 100
• antibody form: purified antibody
• antibody product type: primary antibodies
• clone: 1A10.2, monoclonal
• species reactivity: human
• technique(s): immunohistochemistry: suitable; western blot: suitable
• isotype: IgG2aκ
• NCBI accession no.: NP_006832
• UniProt accession no.: Q99624
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: human ... SLC38A3(10991)

Description

General description

The sodium-coupled neutral amino acid transporter 3 (SLC38A3) protein is a sodium-dependent amino acid/proton exchanger (also called an antiporter or counter transporter) SLC38A3 mediates the electrogenic cotransport of glutamine and sodium ions in exchange for protons. SLC38A3 can also transport the amino acids histidine, asparagine and alanine in place of protons. Some evidence exists that SLC38A3 may mediate amino acid transport in either direction under particular physiological conditions such as homeostatic stress like that seen in acidosis, and SLC38A3 plays a role in nitrogen metabolism and synaptic transmission by regulating the levels of sodium and the stimulatory amino acid glutamine. SLC38A3 is localized to the cell membrane and is widely expressed in many tissues, including heart, liver, brain, and prostate.

Immunogen

GST-tagged recombinant protein corresponding to human SLC38A3.

Application

Anti-SLC38A3 Antibody, clone 1A10.2 | MABN316 is an antibody against SLC38A3 Antibody for use in Western Blotting, Immunohistochemistry.

Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected SLC38A3 in human kidney tissue.

Research Category
Neuroscience

Research Sub Category
Developmental Signaling

Quality

Evaluated by Western Blotting in human kidney tissue lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected SLC38A3 in 10 µg of human kidney tissue lysate.

Target description

~60 kDa observed

Physical form

Format: Purified

Protein G Purified

Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Other Notes

Concentration: Please refer to lot specific datasheet.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1