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Key Documents

QBD10492

Sigma-Aldrich

Aminooxy-dPEG®12-amido-dPEG®12-(m-dPEG®11)3

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About This Item

Empirical Formula (Hill Notation):
C136H270N6O66
Molecular Weight:
3045.60
UNSPSC Code:
51171641
PubChem Substance ID:
NACRES:
NA.22

Assay

>90%

form

solid or viscous liquid

reaction suitability

reagent type: chemical modification reagent
reagent type: cross-linking reagent
reactivity: carbonyl reactive

polymer architecture

shape: branched
functionality: homofunctional

shipped in

ambient

storage temp.

−20°C

SMILES string

O=C(NC(COCCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O)(COCCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O)COCCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCOCCON)=O

Features and Benefits

Aminooxy-dPEG®12-amido-dPEG®12-(m-dPEG®11)3 is a branched dPEG® reagent that is highly useful for protein and peptide modification to increase hydrodynamic volume and serum half-life and to greatly reduce the immunogenicity of the modified peptide or protein. This dPEG® product consists of a linear "tail" with a reactive group, a tris core to provide branching, and methoxy-terminated dPEG® branches. The numbers following dPEG® are the exact number of repeat units in the linear chain. This dPEG® product is hydrophilic, non-immunogenic, single molecular weight compound. The aminooxy functional group reacts with aldehydes and ketones to form oxime bonds.

Legal Information

Products Protected under U.S. Patents # 7,888,536 B2
dPEG is a registered trademark of Quanta BioDesign

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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