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T0195

Sigma-Aldrich

α-Bungarotoxin-tetramethylrhodamine from Bungarus multicinctus (Formosan Banded Krait)

Synonym(s):

TMR-α-BTX

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About This Item

MDL number:
UNSPSC Code:
12352116
NACRES:
NA.77

mol wt

~8,500

Quality Level

color

red

solubility

H2O: soluble

storage temp.

−20°C

Application

α-Bungarotoxin-tetramethylrhodamine from Bungarus multicinctus was used at a dilution of 1:220 to identify the distribution of nicotinic acetylcholine receptors at neuromuscular junctions of longitudinal sections of rat gastrocnemius muscle.
α-Bungarotoxin-tetramethylrhodamine from Bungarus multicinctus (Formosan Banded Krait) has been used in immunofluorescence staining (1:200) for identification of neuromuscular junction in experimental models. It has also been used to block muscle contraction in myotome cells.

Biochem/physiol Actions

α-Bungarotoxin is a high-affinity antagonist for nicotinic acetylcholine receptors (AChRs) from muscle but not the neurons. Labeling α-Bungarotoxin with tetramethylrhodamine enables the detection of bungarotoxin-binding receptors at neuromuscular junctions.
Useful for detecting the distribution of nicotinic acetylcholine receptors at neuromuscular junctions.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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