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Key Documents

RAB0039

Sigma-Aldrich

Cholecystokinin EIA Kit

for serum, plasma, culture supernatant and cell lysates

Synonym(s):

CCK

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About This Item

UNSPSC Code:
41123300
NACRES:
NA.32

species reactivity

rat, mouse, human

technique(s)

ELISA: suitable
enzyme immunoassay: suitable

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... CCK(885)

General description

Cholecystokinin (CCK) belongs to the gastrointestinal hormone family. It is a neuropeptide hormone and neurotransmitter usually present in gastrointestinal (GI) tract and the central nervous system (CNS). It is produced by neurons, and endocrine cells.

Immunogen

Cholecystokinin (CCK), synthetic peptide

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Biochem/physiol Actions

Cholecystokinin (CCK) functions include, trophic effects on pancreas, gall bladder contraction, intestinal motility, and bowel movements. It has roles in various neuropsychiatric and neurological disorders. CCK is satiety peptide and regulates apettite for a short duration. Overproduction of CCK is prominent in metastatic endocrine tumors, and hence it is recognize as a diagnostic marker.

Kit Components Also Available Separately

Product No.
Description
SDS

Pictograms

Corrosion

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Met. Corr. 1

Storage Class Code

8A - Combustible corrosive hazardous materials


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Cholecystokinin: A multi-functional molecular switch of neuronal circuits
Lee SY and Soltesz I
Developmental neurobiology, 71(1), 83-91 (2011)
Postprandial profiles of CCK after high fat and high carbohydrate meals and the relationship to satiety in humans
Gibbons C, et al.
Peptides, 77, 3-8 (2016)
Regulation of Gastrointestinal Mucosal Growth (2010)
Cholecystokinin in plasma predicts cardiovascular mortality in elderly females
Goetze JP, et al.
International Journal of Cardiology, 209, 37-41 (2016)
L I Larsson et al.
Brain research, 165(2), 201-218 (1979-04-13)
Immunocytochemistry and radioimmunochemistry demonstrate the occurrence of the gastrointestinal hormone cholecystokinin (CCK) in both the central and peripheral nervous system of the guinea pig. CCK nerves are particularly numerous in the neocortex, the hippocampus, the amygdaloid nuclei, the hypothalamus, the

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