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Toltrazuril

VETRANAL®, analytical standard

Synonym(s):

1-Methyl-3-{3-methyl-4-[4-(trifluoromethylthio)phenoxy]phenyl}-1,3,5-triazine-2,4,6(1H,3H,5H)-trione, Baycox

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About This Item

Empirical Formula (Hill Notation):
C18H14F3N3O4S
CAS Number:
69004-03-1
Molecular Weight:
425.38
MDL number:
MFCD00867201
UNSPSC Code:
41116107
PubChem Substance ID:
329754744
NACRES:
NA.24

grade

analytical standard

Quality Level

100

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

CN1C(=O)NC(=O)N(C1=O)c2ccc(Oc3ccc(SC(F)(F)F)cc3)c(C)c2

InChI

1S/C18H14F3N3O4S/c1-10-9-11(24-16(26)22-15(25)23(2)17(24)27)3-8-14(10)28-12-4-6-13(7-5-12)29-18(19,20)21/h3-9H,1-2H3,(H,22,25,26)

InChI key

OCINXEZVIIVXFU-UHFFFAOYSA-N

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General description

Toltrazuril is found to be highly effective against coccidia and is used in controlling coccidiosis.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Toltrazuril may be used as a reference standard in the determination of toltrazuril in pork using high-performance liquid chromatography coupled with tandem mass spectrometry (HPLC-MS/MS).

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Environment
GHS09

Signal Word

Warning

Hazard Statements

H410

Precautionary Statements

P273 - P391 - P501

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCL8112
BCCF1934
BCBZ3479
BCBV1965
SZBD233XV

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Toltrazuril effective against a broad spectrum of protozoan parasites
Mehlhorn H, et al.
Parasitology Research, 75(1), 64-66 (1988)
S Cériac et al.
Scientific reports, 9(1), 1237-1237 (2019-02-06)
Resistance to gastro-intestinal nematode (GIN) in small ruminant is expected to arise from protein-rich rather than from energy-rich feeds. The objective of this study was to investigate the effect of the quality of the dietary proteins on the response of
Pd-catalyzed synthesis of Ar-SCF3 compounds under mild conditions.
Georgiy Teverovskiy et al.
Angewandte Chemie (International ed. in English), 50(32), 7312-7314 (2011-06-22)
Aruna Shrestha et al.
Frontiers in microbiology, 11, 983-983 (2020-06-09)
The protozoan parasite Cystoisospora suis causes diarrhea and reduced weight gain in suckling piglets. Infections occur in the first days of life; it is transient but can lead to dysbiosis, exacerbating disease and increasing mortality. Cystoisosporosis is effectively controlled by
Vasilis Skampardonis et al.
Veterinary parasitology, 172(1-2), 46-52 (2010-05-18)
Isospora suis is an important parasitic infection in intensive pig production worldwide, responsible for significant economic losses. In this study the efficacy of toltrazuril treatment against isosporosis was evaluated, under field conditions and throughout the nursing period, in reducing (i)
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