29992

DL-α-Tocopherol acetate

tested according to Ph. Eur.

• Synonym(s): α-Tocopherylis acetas, Vitamin E acetate, all-rac-α-Tocopheryl acetate
• Empirical Formula (Hill Notation): C₃₁H₅₂O₃
• CAS Number: 7695-91-2
• Molecular Weight: 472.74
• Beilstein: 97512
• EC Number: 231-710-0
• MDL number: MFCD00072042
• UNSPSC Code: 12352209
• PubChem Substance ID: 329753404
• NACRES: NA.26

Properties

• biological source: synthetic
• Quality Level: 200
• Agency: USP/NF; tested according to Ph. Eur.
• Assay: 96.5-102.0%
• form: liquid
• density: 0.96 g/mL at 20 °C (lit.)
• application(s): cell analysis; pharmaceutical (small molecule)
• storage temp.: 2-8°C
• SMILES string: CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCc2c(C)c(OC(C)=O)c(C)c(C)c2O1
• InChI: 1S/C31H52O3/c1-21(2)13-10-14-22(3)15-11-16-23(4)17-12-19-31(9)20-18-28-26(7)29(33-27(8)32)24(5)25(6)30(28)34-31/h21-23H,10-20H2,1-9H3/t22-,23-,31-/m1/s1
• InChI key: ZAKOWWREFLAJOT-CEFNRUSXSA-N

Description

General description

α-Tocopherol is a form of vitamin E. Vitamin E can be obtained through dietary sources. RRR‐α‐tocopherol is a natural form of α-Tocopherol.

Application

DL-alpha-Tocopherol acetate was used as a vitamin E supplement for studying whether the addition of an antioxidant or vitamin E in the diet of rats with dextran sulfate sodium (DSS)-induced colitis can reduce detrimental impact of inflammatory bowel disease.

Biochem/physiol Actions

α-Tocopherol is also known as a radical-chain breaker due to its anti-oxidant property.

Tocopherols are lipid soluble anti-oxidants that protect cell membranes from oxidative damage. α-Tocopherol is the form of tocopherol preferentially absorbed by Homosapiens. DL-α-Tocopherol acetate can inhibit oxidation of linoleate.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point(F): No data available
• Flash Point(C): No data available
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves