1.37101

Calcium chloride dihydrate

EMPROVE^® EXPERT, Ph. Eur., BP, JP, USP

• Synonym(s): Calcium dichloride
• Empirical Formula (Hill Notation): CaCl₂ · 2H₂O
• CAS Number: 10035-04-8
• Molecular Weight: 147.01
• MDL number: MFCD00149613
• UNSPSC Code: 12352302
• EC Index Number: 233-140-8

Properties

• Agency: BP; JP; Ph. Eur.; USP
• Quality Level: 500
• product line: EMPROVE^® EXPERT
• form: solid
• pH: 4.5-8.5 (20 °C, 50 g/L in H₂O)
• mp: 176 °C (dec.) (lit.)
• application(s): liquid formulation; ophthalmics; parenterals; pharma/biopharma processes; pharmaceutical
• storage temp.: 15-25°C
• SMILES string: O.O.Cl[Ca]Cl
• InChI: 1S/Ca.2ClH.2H2O/h;2*1H;2*1H2/q+2;;;;/p-2
• InChI key: LLSDKQJKOVVTOJ-UHFFFAOYSA-L

Description

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our EMPROVE^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Calcium chloride dihydrate is a mineral salt typically used as buffering agent in pharmaceutical formulations. Beyond, calcium chloride dihydrate is used as a complexing builder, flavor enhancer and stabilizer for food and beverage.
Due to its low microbial and endotoxin limits, Calcium chloride dihydrate Emprove^® Expert is especially suitable for high-risk applications.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H319
• Precautionary Statements: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Eye Irrit. 2
• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable