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Key Documents

G11802

Sigma-Aldrich

2-Guanidinobenzimidazole

95%

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About This Item

Empirical Formula (Hill Notation):
C8H9N5
CAS Number:
Molecular Weight:
175.19
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

95%

mp

242-244 °C (dec.) (lit.)

SMILES string

NC(=N)Nc1nc2ccccc2[nH]1

InChI

1S/C8H9N5/c9-7(10)13-8-11-5-3-1-2-4-6(5)12-8/h1-4H,(H5,9,10,11,12,13)

InChI key

JJWCTKUQWXYIIU-UHFFFAOYSA-N

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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S Friis et al.
The Journal of membrane biology, 184(3), 291-297 (2002-03-14)
In this communication we show that Gd3+ acts as an activator of the apical sodium channel (ENaC) in frog skin epithelia. Application of Gd3+ to the apical solution of frog skin epithelia increased the Na+ absorption measured as the amiloride-inhibitable
P Komwatana et al.
The Journal of membrane biology, 162(3), 225-232 (1998-05-16)
We have previously shown that epithelial Na+ channels in mouse mandibular gland duct cells are controlled by cytosolic Na+ and Cl-, acting, respectively, via Go and Gi proteins. Since we found no evidence for control of epithelial Na+ channels by
Chang Zhao et al.
Communications biology, 4(1), 261-261 (2021-02-28)
Here, we report the identification and characterization of the first proton channels from fungi. The fungal proteins are related to animal voltage-gated Hv channels and are conserved in both higher and lower fungi. Channels from Basidiomycota and Ascomycota appear to
M Fronius et al.
The Journal of membrane biology, 195(1), 43-51 (2003-09-23)
In the present study we investigated the effect of extracellular gadolinium on amiloride-sensitive Na(+) current across Xenopus alveolar epithelium by Ussing chamber experiments and studied its direct effect on epithelial Na(+) channels with the patch-clamp method. As observed in various
K Eskesen et al.
Acta physiologica Scandinavica, 136(4), 547-550 (1989-08-01)
Serosal amiloride inhibits Na+, K+ and Cl- efflux and reduces short-circuit current and transepithelial conductance in noradrenaline-stimulated frog skin in which the sodium channels in the apical membrane are blocked by amiloride. BIG (benzimidazoleguanidine) inhibits Na+ and K+ efflux and

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