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C8527

Sigma-Aldrich

Chlorhexidine dihydrochloride

≥98%

Synonym(s):

1,6-Bis(N5-[p-chlorophenyl]-N1-biguanido)hexane; 1,1′-Hexamethylenebis(5-[p-chlorophenyl]biguanide), Lisium

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About This Item

Empirical Formula (Hill Notation):
C22H30Cl2N10 · 2HCl
CAS Number:
Molecular Weight:
578.37
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

≥98%

form

powder

storage temp.

2-8°C

SMILES string

Cl.Clc1ccc(NC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)Nc2ccc(Cl)cc2)cc1

InChI

1S/C22H30Cl2N10.2ClH/c23-15-5-9-17(10-6-15)31-21(27)33-19(25)29-13-3-1-2-4-14-30-20(26)34-22(28)32-18-11-7-16(24)8-12-18;;/h5-12H,1-4,13-14H2,(H5,25,27,29,31,33)(H5,26,28,30,32,34);2*1H

InChI key

WJLVQTJZDCGNJN-UHFFFAOYSA-N

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Steven P Engebretson et al.
JAMA, 310(23), 2523-2532 (2013-12-19)
Chronic periodontitis, a destructive inflammatory disorder of the supporting structures of the teeth, is prevalent in patients with diabetes. Limited evidence suggests that periodontal therapy may improve glycemic control. To determine if nonsurgical periodontal treatment reduces levels of glycated hemoglobin
C M Martín-Navarro et al.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 251(9), 2111-2117 (2013-05-21)
Acanthamoeba is an opportunistic pathogen which is the causal agent of a sight-threatening ulceration of the cornea known as "Acanthamoeba keratitis" (AK) and, more rarely, an infection of the central nervous system called "granulomatous amoebic encephalitis" (GAE). The symptoms of
Nasia Safdar et al.
Critical care medicine, 42(7), 1703-1713 (2014-03-29)
To assess the efficacy of a chlorhexidine-impregnated dressing for prevention of central venous catheter-related colonization and catheter-related bloodstream infection using meta-analysis. Multiple computerized database searches supplemented by manual searches including relevant conference proceedings. Randomized controlled trials evaluating the efficacy of
Hiroshi Kinashi et al.
Journal of the American Society of Nephrology : JASN, 24(10), 1627-1642 (2013-08-31)
Peritoneal fibrosis (PF) causes ultrafiltration failure (UFF) and is a complicating factor in long-term peritoneal dialysis. Lymphatic reabsorption also may contribute to UFF, but little is known about lymphangiogenesis in patients with UFF and peritonitis. We studied the role of
Rengin Attin et al.
Australian orthodontic journal, 29(1), 52-57 (2013-06-22)
The aim of this prospective study was to evaluate the re-colonisation pattern of Streptococcus mutans (MS) in highlevel MS-colonised patients with fixed orthodontic appliances following 40% chlorhexidine varnish application prior to bracket placement. The subjects of this single-blinded clinical trial

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