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900927

Sigma-Aldrich

TCO-PNB ester

≥95%

Synonym(s):

(1R,4E)-4-Cycloocten-1-yl 4-nitrophenyl carbonate, rel-(1R-4E-PS)-cyclooct-4-en-1-yl (4-nitrophenyl) carbonate

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About This Item

Empirical Formula (Hill Notation):
C15H17NO5
CAS Number:
1438415-89-4
Molecular Weight:
291.30
UNSPSC Code:
12352108
NACRES:
NA.22

Quality Level

100

Assay

≥95%

form

powder or chunks

reaction suitability

reaction type: click chemistry
reagent type: cross-linking reagent

storage temp.

−20°C

SMILES string

O=C(OC1CCC/C=C/CC1)OC2=CC=C([N+]([O-])=O)C=C2

Related Categories

Application

TCO-PNB ester (trans-Cyclooctene-p-nitrobenzyl ester) has a p-nitrobenzyl (PNB) ester group that is amine reactive and a trans-cyclooctene (TCO) group that is reactive with tetrazines. TCO-PNB ester is supplied as a single axial (major) diastereomer. This specially formulated crystalline material provides easy handling and extended shelf life.

related product

Product No.
Description
Pricing

924083

TAMRA-a-TCO

924091

Alkyne-a-TCO

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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Imaging cell surface glycosylation in vivo using ?double click? chemistry.
Neves A A, et al.
Bioconjugate Chemistry, 24(6), 934-941 (2013)

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