471070

3,5-Bis(trifluoromethyl)phenylboronic acid

≥95%

• Synonym(s): 3,5-Di(trifluoromethyl)benzeneboronic acid
• Linear Formula: (CF₃)₂C₆H₃B(OH)₂
• CAS Number: 73852-19-4
• Molecular Weight: 257.93
• Beilstein: 7379990
• MDL number: MFCD00051850
• UNSPSC Code: 12352103
• PubChem Substance ID: 24870695
• NACRES: NA.22

Properties

• Assay: ≥95%
• form: powder
• mp: 217-220 °C (lit.)
• SMILES string: OB(O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F
• InChI: 1S/C8H5BF6O2/c10-7(11,12)4-1-5(8(13,14)15)3-6(2-4)9(16)17/h1-3,16-17H
• InChI key: BPTABBGLHGBJQR-UHFFFAOYSA-N

Description

Application

Reactant involved in the synthesis of:

• Methylene-arylbutenones via carbonylative arylation of allenols
• 4-aminoquinoline analogs via Ullman / Suzuki / Negishi coupling
• Primary amino acid derivatives with anticonvulsant activity
• Alkyl arylcarbamates via Cu-catalyzed coupling with potassium cyanate
• Aryl-substituted succinimides and cyclic ketones by asymmetric conjugate addition
• Axially chiral dicarboxylic acids for asymmetric Mannich-type reactions

Other Notes

Contains varying amounts of anhydride

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves