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324787

Sigma-Aldrich

2,2,2-Trifluoroethanesulfonyl chloride

99%

Synonym(s):

Tresyl chloride

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About This Item

Linear Formula:
CF3CH2SO2Cl
CAS Number:
Molecular Weight:
182.55
Beilstein:
1860983
EC Number:
MDL number:
UNSPSC Code:
12352101
PubChem Substance ID:
NACRES:
NA.22
Pricing and availability is not currently available.

Assay

99%

form

liquid

refractive index

n20/D 1.388 (lit.)

bp

140-141 °C (lit.)
64-67 °C/45 mmHg (lit.)

density

1.651 g/mL at 25 °C (lit.)

functional group

fluoro

storage temp.

2-8°C

SMILES string

FC(F)(F)CS(Cl)(=O)=O

InChI

1S/C2H2ClF3O2S/c3-9(7,8)1-2(4,5)6/h1H2

InChI key

CXCHEKCRJQRVNG-UHFFFAOYSA-N

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Pictograms

Corrosion

Signal Word

Danger

Hazard Statements

Hazard Classifications

Skin Corr. 1B

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Flash Point(F)

161.6 °F - closed cup

Flash Point(C)

72 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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K I Allam et al.
Analytical biochemistry, 162(1), 171-177 (1987-04-01)
A stable T-2 hydrazide gel is prepared by activating T-2 toxin with tresyl chloride followed by coupling to agarose-adipic acid hydrazide. Utilized as an affinity chromatography column, this T-2 hydrazide gel purifies a monoclonal antibody for T-2 in high yield
Annie Chen et al.
Langmuir : the ACS journal of surfaces and colloids, 25(23), 13510-13515 (2009-11-26)
A 10-fold improvement in the signal-to-noise (S/N) ratio of an optically encoded silica particle-based immunoassay was achieved through incorporating a protein resistant poly(ethylene glycol) (PEG) surface layer and optimizing antibody immobilization conditions. PEG was activated using 2,2,2-trifluoroethanesulfonyl chloride (tresyl) and
Jie Mei et al.
Electrophoresis, 29(18), 3825-3833 (2008-08-30)
A novel covalent coupling method for coating of capillaries with liposomes has been developed, which includes three steps: (i) epoxy-diol coating, (ii) activation with 2,2,2-trifluoroethanesulfonyl chloride, and (iii) liposome coupling. The coating conditions, such as the reaction time and temperature
K Nakamura et al.
Journal of chromatography, 510, 101-113 (1990-06-27)
A new activated support TSK gel Tresyl-5PW was evaluated for the coupling of antibodies, which was found to occur easily under mild conditions with high yields. Optimum coupling conditions were a 2-h reaction at 25 degrees C in 1 M
C F Mandenius et al.
Analytical biochemistry, 137(1), 106-114 (1984-02-01)
Two methods for the chemical binding of biomolecules to silicon surfaces are described. The first method utilizes an alkyl silane and a nucleophilic reagent to join the biomolecule to the silicon surface; the second method involves crosslinking with glutaraldehyde in

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