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8.52384

Sigma-Aldrich

Fmoc-Lys(Boc)-Cys(psiDmp,Hpro)-OH

Novabiochem®

Synonym(s):

Fmoc-Lys(Boc)-Cys(psiDmp,Hpro)-OH

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About This Item

Empirical Formula (Hill Notation):
C39H47N3O9S
Molecular Weight:
733.87
UNSPSC Code:
12352209
NACRES:
NA.22

Quality Level

product line

Novabiochem®

form

powder

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

application(s)

peptide synthesis

functional group

thiol

storage temp.

15-25°C

General description

A cysteine-based pseudoproline dipeptide. It prevents aggregation during Fmoc SPPS and enhances product purity in an identical manner to standard pseuproline dipeptides. The pseudoproline ring is cleaved with TFA, regenerating the native Cys residue.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Overcoming Aggregation in Fmoc SPPS

Analysis Note

Colour (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity Cysteine: ≥ 99.5 % (a/a)
Enantiomeric purity second amino acid: ≥ 99.0 % (a/a)
Purity (TLC(157A)): ≥ 97 %
Purity (TLC(CMA2)): ≥ 97 %
Assay (HPLC, area%): ≥ 97.0 % (a/a)
Ethyl acetate (HS-GC): ≤ 0.50 %
Acetate (IC): ≤ 0.05

To see the solvent systems used for TLC of Novabiochem® products please click here.
The product is a racemic mixture.

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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