5711

Streptomycin Sulfate

from Streptomyces sp., Bacterial protein synthesis inhibitor, powder

• Synonym(s): Streptomycin Sulfate, Streptomyces sp.
• CAS Number: 3810-74-0
• UNSPSC Code: 51281624
• NACRES: NA.77
• MDL number: MFCD00037023
• Form: powder
• Storage condition: OK to freeze

Properties

• Product Name: Streptomycin Sulfate, Streptomyces sp.,
• form: powder
• Quality Segment: 100
• specific activity: ≥720 IU/g (dry basis)
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze
• color: white to off-white
• shipped in: ambient
• storage temp.: 2-8°C
• SMILES string: [S](=O)(=O)(O)O.[S](=O)(=O)(O)O.[S](=O)(=O)(O)O.N([C@@H]4[C@@H](O[C@H]([C@@H]([C@H]4O)O)CO)O[C@H]5[C@@H](O[C@H]([C@]5(O)C=O)C)O[C@@H]6[C@H]([C@@H]([C@H]([C@@H]([C@H]6O)O)N=C(N)N)O)N=C(N)N)C.N([C@@H]1[C@@H](O[C@H]([C@@H]([C@H]1O)O)CO)O[C@H]2[C@@H](O[C@H]([
• InChI: 1S/2C21H39N7O12.3H2O4S/c2*1-5-21(36,4-30)16(40-17-9(26-2)13(34)10(31)6(3-29)38-17)18(37-5)39-15-8(28-20(24)25)11(32)7(27-19(22)23)12(33)14(15)35;3*1-5(2,3)4/h2*4-18,26,29,31-36H,3H2,1-2H3,(H4,22,23,27)(H4,24,25,28);3*(H2,1,2,3,4)/t2*5-,6-,7+,8-,9-,10-,11+,12-,13-,14+,15+,16-,17-,18-,21+;;;/m00.../s1
• InChI key: QTENRWWVYAAPBI-YCRXJPFRSA-N

Description

General description

Antibiotic effective against Gram-positive and Gram-negative bacteria. Often used in culture media to control growth of microorganisms. Inhibits initiation, elongation, and termination of protein synthesis in prokaryotes and induces misreading of the genetic code.

Antibiotic effective against gram-positive and gram-negative bacteria. Often used in culture media to control the growth of microorganisms. Inhibits initiation, elongation, and termination of protein synthesis in prokaryotes and induces misreading of the genetic code. Suggested working concentration: 25-50 µg/ml.

Biochem/physiol Actions

Primary Target
initiation, elongation, and termination of protein synthesis in prokaryotes and induces misreading of the genetic code

Preparation Note

Autoclaved media should be cooled to ≤55°C before adding streptomycin.

Following reconstitution, sterilize by filtration through a 0.22 µm pore-size filter, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Lech, K. and Brent, R. 1995. in Current Protocols in Molecular Biology, Vol. 1 (Ausubel, F.M., et al., eds.), John Wiley & Sons, New York Unit 1.4.
Maniatis, T., et al. 1989. In Molecular Cloning, A Laboratory Manual, Second Edition. Cold Spring Harbor, New York, p. A.6.
Modolell, J. and Davis, B.D. 1969. Nature224, 345.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Carcinogenic / Teratogenic (D)

Safety Information

• Pictograms: GHS08,GHS07
• Signal Word: Warning
• Hazard Codes: H302,H361fd
• Precautionary Statements: P202 - P264 - P270 - P280 - P301 + P312 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Repr. 2
• Storage Class: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable