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G-001

Supelco

GHB sodium salt solution

1.0 mg/mL in methanol (as salt), ampule of 1 mL, certified reference material, Cerilliant®

Synonym(s):

4-Hydroxybutyric acid sodium salt solution

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About This Item

Empirical Formula (Hill Notation):
C4H7NaO3
CAS Number:
502-85-2
Molecular Weight:
126.09
EC Number:
200-659-6
MDL number:
MFCD00004402
UNSPSC Code:
41116107
NACRES:
NA.24

grade

certified reference material

Quality Level

300

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

drug control

Narcotic Licence Schedule A (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IIA (Portugal)

concentration

1.0 mg/mL in methanol (as salt)

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

forensics and toxicology

format

single component solution

storage temp.

−20°C

SMILES string

OCCCC([O-])=O.[Na+]

InChI

1S/C4H8O3/c5-3-1-2-4(6)7/h5H,1-3H2,(H,6,7)/p-1

InChI key

SJZRECIVHVDYJC-UHFFFAOYSA-M

General description

GHB, or γ-hydroxybutyrate, is a central nervous system depressant sold under the brand name Xyrem® and used medically to treat narcolepsy, excessive daytime sleepiness and in rare circumstances, alcoholism. GHB is also used recreationally as an intoxicant and date rape drug. Its many street names include “GBH”, “Liquid X”, “G”, “Juice”, and “Mils”.

Application


  • GHB sodium salt in sleep disorder research: A study on nocturnal sodium oxybate, a form of GHB sodium salt, revealed an increase in the anterior cingulate cortex magnetic resonance glutamate signal upon awakening, suggesting its potential application in modulating brain function in sleep research (Dornbierer et al., 2023).

  • Investigation of GHB Na+ in alcohol-addiction treatment: Research focusing on the effect of the sodium salt of gamma-hydroxybutyrate (GHB) for alcohol-addiction treatment, it is effective in maintaining abstinence, with less craving for alcohol and lower rates of relapse (Frisoni et al., 2023).

  • Gamma-hydroxybutyrate sodium for in vitro biochemical assays: A detailed study on the pharmacokinetics and metabolism of gamma-hydroxybutyrate (GHB) in rats perturbed by alcohol, offers a model for in vitro studies examining GHB′s biochemical behavior and interaction with alcohol (Kim et al., 2023).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
Xyrem is a registered trademark of JPI Commercial, LLC

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Target Organs

Eyes

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

49.5 °F - closed cup

Flash Point(C)

9.7 °C - closed cup

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Maria Maj Jensen et al.
Ugeskrift for laeger, 174(25), 1749-1750 (2012-06-21)
Gammahydroxybutyrate (GHB) is also known as fantasy or liquid ecstasy. Its use as a recreational drug has been illegal in Denmark since 1999. However, the GHB pro-drug gammabutyrolactone (GBL) is available to everybody since it is the main ingredient in
Franklyn H Geary et al.
Clinical obstetrics and gynecology, 56(1), 166-172 (2013-02-02)
The drug abusing patient can provide a management dilemma for health care providers including nurses, obstetrician, anesthesiologist, and pediatrician. Certain illicit drugs may mimic other diseases of pregnancy and result in inappropriate treatment for the mother and child. Pain management
Shilpa R Kauta et al.
Pediatric neurology, 47(5), 362-365 (2012-10-10)
Narcolepsy is characterized by recurrent brief attacks of irresistible sleepiness. Signs can begin during childhood. However, diagnoses are frequently delayed by 10-15 years because of unfamiliarity with pediatric narcolepsy and variable presentations of its associated features (cataplexy, hypnagogic/hypnopompic hallucinations, and
John M Roll et al.
Journal of the experimental analysis of behavior, 97(3), 323-331 (2012-06-14)
Gamma-hydroxybutyrate (GHB) is a drug with significant abuse potential. The present study aimed to assess the relative value of escalating doses of GHB to current GHB users via the Multiple Choice Procedure (MCP), and to validate that the dose rated
Jae Seong Lee et al.
Journal of biotechnology, 161(1), 34-41 (2012-06-26)
Previous research showed that co-down-regulation of caspase-3/7 in rCHO cells, unlike Bcl-2 overexpression, did not effectively block apoptotic cell death induced by 3mM sodium butyrate (NaBu). Here, it is found that the control of autophagy is also related to this
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