Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

164534

Sigma-Aldrich

Trimethyl orthobenzoate

98%

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
C6H5C(OCH3)3
CAS Number:
707-07-3
Molecular Weight:
182.22
EC Number:
211-897-5
MDL number:
MFCD00008474
UNSPSC Code:
12352100
PubChem Substance ID:
24850081
NACRES:
NA.22

Quality Level

100

Assay

98%

form

liquid

refractive index

n20/D 1.489 (lit.)

bp

87-88 °C/7 mmHg (lit.)

density

1.061 g/mL at 25 °C (lit.)

SMILES string

COC(OC)(OC)c1ccccc1

InChI

1S/C10H14O3/c1-11-10(12-2,13-3)9-7-5-4-6-8-9/h4-8H,1-3H3

InChI key

IECKAVQTURBPON-UHFFFAOYSA-N

General description

Trimethyl orthobenzoate reacts with P-dimethylaminophosphonic acid bis(1-methylhydrazide) to yield 1,2,5,6-tetrahydro-1,5-dimethyl-6-(N,N-dimethylamino)-6-phenyl-1,2,4,5,6-tetrazaphosphorine-6-oxide.

Application

Trimethyl orthobenzoate was used in the preparation of 5-phenyl-4,6-dipyrrin and 2,3-orthoester derivatives of ethyl-1-thio-α-L-rhamnopyranoside.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

179.6 °F - closed cup

Flash Point(C)

82 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 1

1 of 1

2,2-Dimethoxypropane reagent grade, 98%

Sigma-Aldrich

D136808

2,2-Dimethoxypropane

R G Hicks et al.
Inorganic chemistry, 40(8), 1865-1870 (2001-04-21)
Reaction of P-dimethylaminophosphonic acid bis(1-methylhydrazide) (6) with trimethyl orthobenzoate gave 1,2,5,6-tetrahydro-1,5-dimethyl-6-(N,N-dimethylamino)-6-phenyl-1,2,4,5,6-tetrazaphosphorine-6-oxide (7), which was subsequently oxidized to the corresponding P-diemthylamino-6-phosphaverdazyl (5) as a persistent radical. Analysis of the electron paramagnetic resonance spectrum of 5 revealed significant spin density on the
Incidence and avoidance of stereospecific 1, 2-ethylthio group migration during the synthesis of ethyl 1-thio-a-l-rhamnopyranoside 2, 3-orthoester.
Auzanneau F-I and Bundle DR.
Carbohydrate Research, 212, 13-24 (1991)
Reactions between pyrrole and orthoesters: preparation of tri-(pyrrol-2-yl) alkanes.
Reese CB and Yan H.
Tetrahedron Letters, 43(32), 5545-5547 (2001)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service