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  • Antifungal activity of transparent nanocomposite thin films of pullulan and silver against Aspergillus niger.

Antifungal activity of transparent nanocomposite thin films of pullulan and silver against Aspergillus niger.

Colloids and surfaces. B, Biointerfaces (2012-12-04)
Ricardo J B Pinto, Adelaide Almeida, Susana C M Fernandes, Carmen S R Freire, Armando J D Silvestre, Carlos Pascoal Neto, Tito Trindade
ABSTRACT

Silver has been mainly investigated as an antibacterial agent and less as a fungicide in which concerns antimicrobial properties. In this research, the antifungal activity of composite films of pullulan and Ag nanoparticles (NP) against Aspergillus niger was evaluated using standard protocols. These new materials were prepared as transparent cast films (66-74 μm thickness) from Ag hydrosols containing the polysaccharide. Fungal growth inhibition was observed in the presence of such silver nanocomposite films. Moreover, disruption of the spores cells of A. niger was probed for the first time by means of scanning electron microscopy (SEM). This effect occurred in the presence of the nanocomposites due to Ag NP dispersed as fillers in pullulan. This polysaccharide was used here as a biocompatible matrix, hence making these nanocomposites beneficial for the development of antifungal packaging materials.

MATERIALS
Product Number
Brand
Product Description

Supelco
Pullulan Standard Set Mp ~350 - 700′000, set of analytical standards, for GPC
Sigma-Aldrich
Pullulan, suitable for substrate for pullulanase