1713004

Vinblastine sulfate

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): Vinblastine sulfate salt, Vincaleukoblastine, Sulfate (1:1) (salt), VLB, Vincaleukoblastine sulfate salt
• Empirical Formula (Hill Notation): C₄₆H₅₈N₄O₉ · H₂SO₄
• CAS Number: 143-67-9
• Molecular Weight: 909.05
• Beilstein: 3659812
• MDL number: MFCD00082457
• UNSPSC Code: 41116107
• PubChem Substance ID: 329751498
• NACRES: NA.24

Properties

• grade: pharmaceutical primary standard
• API family: vinblastine
• manufacturer/tradename: USP
• mp: 267 °C (dec.) (lit.)
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: −20°C
• SMILES string: OS(O)(=O)=O.[H][C@@]12CN(CCc3c([nH]c4ccccc34)[C@@](C1)(C(=O)OC)c5cc6c(cc5OC)N(C)[C@@]7([H])[C@](O)([C@H](OC(C)=O)[C@]8(CC)C=CCN9CC[C@]67[C@]89[H])C(=O)OC)C[C@](O)(CC)C2
• InChI: 1S/C46H58N4O9.H2O4S/c1-8-42(54)23-28-24-45(40(52)57-6,36-30(15-19-49(25-28)26-42)29-13-10-11-14-33(29)47-36)32-21-31-34(22-35(32)56-5)48(4)38-44(31)17-20-50-18-12-16-43(9-2,37(44)50)39(59-27(3)51)46(38,55)41(53)58-7;1-5(2,3)4/h10-14,16,21-22,28,37-39,47,54-55H,8-9,15,17-20,23-26H2,1-7H3;(H2,1,2,3,4)/t28-,37-,38+,39+,42-,43+,44+,45-,46-;/m0./s1
• InChI key: KDQAABAKXDWYSZ-PNYVAJAMSA-N
• Gene Information: human ... TUBA1A(7846) , TUBA1B(10376) , TUBA1C(84790) , TUBA3C(7278) , TUBA3E(112714) , TUBA4A(7277) , TUBB(203068) , TUBB1(81027) , TUBB2A(7280) , TUBB2B(347733) , TUBB3(10381) , TUBB4A(10382) , TUBB4B(10383) , TUBB6(84617) , TUBB8(347688)

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Vinblastine sulfate USP reference standard for use in specified quality tests and assays.

Also used to prepare standard and system suitability solutions for the assay, according to the given below monographs of United States Pharmacopeia (USP):

• Vinblastine Sulfate[1]
• Vincristine Sulfate[2]
• Vinblastine Sulfate for Injection[3]
• Vincristine Sulfate for Injection[4]
• Vincristine Sulfate Injection[5]

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Safety Information

• Pictograms: GHS08,GHS07
• Signal Word: Warning
• Hazard Statements: H302,H341,H361fd
• Precautionary Statements: P202 - P264 - P280 - P301 + P312 - P308 + P313 - P405
• Hazard Classifications: Acute Tox. 4 Oral - Muta. 2 - Repr. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3