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1677002

USP

Triamcinolone acetonide

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

9α-Fluoro-11β,16α,17α,21-tetrahydroxy-1,4-pregnadiene-3,20-dione 16,17-acetonide, 9α-Fluoro-16α-hydroxyprednisolone 16α,17α-acetonide

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About This Item

Empirical Formula (Hill Notation):
C24H31FO6
CAS Number:
Molecular Weight:
434.50
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

triamcinolone

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

[H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1(F)[C@@H](O)C[C@@]4(C)[C@@]2([H])C[C@H]5OC(C)(C)O[C@@]45C(=O)CO

InChI

1S/C24H31FO6/c1-20(2)30-19-10-16-15-6-5-13-9-14(27)7-8-21(13,3)23(15,25)17(28)11-22(16,4)24(19,31-20)18(29)12-26/h7-9,15-17,19,26,28H,5-6,10-12H2,1-4H3/t15-,16-,17-,19+,21-,22-,23-,24+/m0/s1

InChI key

YNDXUCZADRHECN-JNQJZLCISA-N

Gene Information

human ... NR3C1(2908)

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Triamcinolone acetonide USP reference standard intended for use in specified quality tests and assays.

Also used to prepare system suitability, standard, and standard stock solution for assay, impurity analysis, and performance tests according to the given below monographs of United States Pharmacopeia (USP):
  • Triamcinolone Hexacetonide
  • Triamcinolone Acetonide Injectable Suspension
  • Triamcinolone Acetonide Nasal Spray

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Pictograms

Health hazardExclamation mark

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Repr. 1B

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Triamcinolone Acetonide Nasal Spray
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 46(5) (2021)
Triamcinolone Acetonide Injectable Suspension
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 44(3), 4490-4490 (2020)
Triamcinolone Hexacetonide
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 36(5), 4492-4492 (2020)
Jost B Jonas
Ophthalmic research, 38(4), 218-245 (2006-06-10)
Based on experimental studies and clinical observations by Robert Machemer, Gholam Peyman and others, the vitreous cavity has increasingly been used as a reservoir of drugs for the direct treatment of intraocular diseases. The most widely injected drug so far
E M Becerra et al.
Current drug targets, 12(2), 149-172 (2010-10-05)
Triamcinolone acetonide (TA) is one of the first pharmacologic compounds evaluated for the treatment of choroidal neovascularization (CNV) secondary to age-related macular degeneration (AMD). The most important effects of TA consist in the stabilisation of the blood-retinal barrier and the

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