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SMB00509

Sigma-Aldrich

1,2-Dimyristoyl-sn-glycerol

≥95%

Synonym(s):

(S)-1,2-Dimyristin, (S)-Glycerol 1,2-dimyristate, 1,2-Ditetradecanoyl-sn-glycerol, DMG

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About This Item

Empirical Formula (Hill Notation):
C31H60O5
CAS Number:
Molecular Weight:
512.81
Beilstein:
1808871
MDL number:
UNSPSC Code:
12352211
PubChem Substance ID:
NACRES:
NA.25

biological source

synthetic (organic)

Quality Level

Assay

≥95%

form

powder

functional group

ketone

lipid type

neutral glycerides

storage temp.

2-8°C

SMILES string

CCCCCCCCCCCCCC(OC[C@H](CO)OC(CCCCCCCCCCCCC)=O)=O

InChI

1S/C31H60O5/c1-3-5-7-9-11-13-15-17-19-21-23-25-30(33)35-28-29(27-32)36-31(34)26-24-22-20-18-16-14-12-10-8-6-4-2/h29,32H,3-28H2,1-2H3/t29-/m0/s1

InChI key

JFBCSFJKETUREV-LJAQVGFWSA-N

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Application

1,2-Dimyristoyl-sn-glycerol (1,2-ditetradecanoyl-sn-glycerol) may be used as a reactant in the preparation of 1,2-[13,13-2H2]dimyristoyl-sn-glycero-3-phosphoethanolamine and sodium 1,2-ditetradecanoyl-sn-glycer-3-yl phenyl phosphate.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Proceedings of the National Academy of Sciences of the United States of America, 114(10), E1941-E1950 (2017-02-17)
Safe and efficient delivery of messenger RNAs for protein replacement therapies offers great promise but remains challenging. In this report, we demonstrate systemic, in vivo, nonviral mRNA delivery through lipid nanoparticles (LNPs) to treat a Factor IX (
Dynamic structure and phase behavior of dimyristoylphosphatidylethanolamine bilayers studied by deuterium nuclear magnetic resonance.
Marsh D, et al.
Biochemistry, 22(12), 3023-3026 (1983)
V Micol et al.
Biophysical journal, 76(2), 916-927 (1999-02-04)
Lipid activation of protein kinase C alpha (PKC alpha) was studied by using a model mixture containing 1, 2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC), 1, 2-dimyristoyl-sn-glycero-3-phosphoserine (DMPS), and 1, 2-dimyristoyl-sn-glycerol (1,2-DMG). This lipid mixture was physically characterized by differential scanning calorimetry (DSC), Fourier transform

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