SAB5700411

Anti-Phospho-PDGFRA-Y849 antibody produced in rabbit

• Synonym(s): CD140A, GAS9, PDGFR-2, PDGFR2, PDGFRA, RHEPDGFRA
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: 122; 24; 82
• species reactivity: human
• concentration: 2.21 mg/ml
• technique(s): western blot: 1:500-1:2000
• UniProt accession no.: P16234
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: phosphorylation (pTyr849)
• Gene Information: human ... PDGFRA(5156)

Description

General description

This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.

Immunogen

A synthetic phosphorylated peptide around Y849 of human PDGFRA (NP_006197.1).

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Storage and Stability

Store at -20℃. Avoid freeze / thaw cycles.

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable