Peptide sequence around aa. 297-301 (G-E-Y-A-V), according to the protein DOK2.
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Target description
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK2 may modulate the cellular proliferation induced by IL-4, as well as IL-2 and IL-3. May be involved in modulating Bcr-Abl signaling. Attenuates EGF-stimulated MAP kinase activation.
Physical form
Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol
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