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S0702

Sigma-Aldrich

Shikimate-3-Phosphate Trisodium Salt

EPSP synthase substrate

Synonym(s):

3-phosphoshikimic acid trisodium salt, Shikimic acid 3-phosphate trisodium salt

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About This Item

UNSPSC Code:
12352204
NACRES:
NA.54

product name

Shikimate-3-Phosphate Trisodium Salt,

solubility

H2O: 1.0 mg/mL

storage temp.

−20°C

Related Categories

General description

Shikimate-3-Phosphate acts as an intermediate in the shikimic acid pathway of aromatic amino acid biosynthesis in microorganisms.

Application

Substrate for EPSP synthase, an enzyme involed in amino acid synthesis as well as glyphosate resistance in GMO crops.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Ri-He Peng et al.
PloS one, 7(8), e39579-e39579 (2012-08-08)
The 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS; EC 2.5.1.19) is a key enzyme in the shikimate pathway for the production of aromatic amino acids and chorismate-derived secondary metabolites in plants, fungi, and microorganisms. It is also the target of the broad-spectrum herbicide glyphosate.
The formation of shikimate-3-phosphate in cell-free preparations of Sorghum
Bowen JR and Kosuge T
Phytochemistry, 16(7), 881-884 (1977)
Meng Xie et al.
The Plant cell, 30(7), 1645-1660 (2018-06-13)
Long-lived perennial plants, with distinctive habits of inter-annual growth, defense, and physiology, are of great economic and ecological importance. However, some biological mechanisms resulting from genome duplication and functional divergence of genes in these systems remain poorly studied. Here, we

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