R4892
Ranakinin
≥97% (HPLC)
Synonym(s):
Lys-Pro-Asn-Pro-Glu-Arg-Phe-Tyr-Gly-Leu-Met-NH2
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About This Item
Empirical Formula (Hill Notation):
C62H95N17O15S
CAS Number:
Molecular Weight:
1350.59
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
Assay
≥97% (HPLC)
storage temp.
−20°C
SMILES string
CSCCC(NC(=O)C(CC(C)C)NC(=O)CNC(=O)C(Cc1ccc(O)cc1)NC(=O)C(Cc2ccccc2)NC(=O)C(CCCNC(N)=N)NC(=O)C(CCC(O)=O)NC(=O)C3CCCN3C(=O)C(CC(N)=O)NC(=O)C4CCCN4C(=O)C(N)CCCCN)C(N)=O
Biochem/physiol Actions
NK1 tachykinin receptor agonist
Other Notes
Originally isolated from the brain of frog, Rana ridibunda
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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T Badgery-Parker et al.
Peptides, 14(4), 771-775 (1993-07-01)
The tachykinin binding site preferences of neuropeptide gamma (NP gamma), its C-terminal fragments AcNP gamma(3-21), AcNP gamma(5-21), AcNP gamma(7-21), and AcNP gamma(9-21), other mammalian tachykinins, and the nonmammalian tachykinins ranakinin and carassin were examined in membrane binding competition studies. [125I]-Bolton-Hunter
F O'Harte et al.
Journal of neurochemistry, 57(6), 2086-2091 (1991-12-01)
An extract of the whole brain of the frog Rana ridibunda contained high concentrations of substance P-like immunoreactivity, measured with an antiserum directed against the COOH-terminal region of mammalian substance P and neurokinin B-like immunoreactivity, measured with an antiserum directed
M K Kodjo et al.
Endocrinology, 136(8), 3253-3259 (1995-08-01)
The adrenal gland of the frog is innervated by a network of fibers containing two tachykinins (ranakinin and [Leu3,Ile7]neurokinin A), which both stimulate corticosteroid secretion from frog adrenal tissue. The aim of the present study was to determine the mode
M K Kodjo et al.
The Journal of steroid biochemistry and molecular biology, 57(5-6), 329-335 (1996-03-01)
It has recently been shown that the adrenal gland of the frog Rana ridibunda is densely innervated by a network of fibers containing two novel tachykinins, i.e. ranakinin (the counterpart of substance P) and [Leu3, Ile7]neurokinin A. Both ranakinin and
Xiuhong Liu et al.
Journal of peptide science : an official publication of the European Peptide Society, 14(5), 626-630 (2007-11-13)
A bradykinin-like peptide has been isolated from the skin secretions of the frog Rana nigrovittata. This peptide was named ranakinin-N. Its primary structure, RAEAVPPGFTPFR, was determined by Edman degradation and mass spectrometry. It is structurally related to bradykinin-like peptides identified
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