P6762
Poly-L-aspartic acid sodium salt
mol wt 15,000-50,000
Synonym(s):
Poly(L-aspartic acid) sodium salt
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About This Item
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mol wt
15,000-50,000
storage temp.
−20°C
SMILES string
NC(CC(O)=O)C(=O)O[Na]
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Analysis Note
Molecular weight based on viscosity.
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Anna Kubíčková et al.
Physical review letters, 108(18), 186101-186101 (2012-06-12)
Charge reversal as an extreme case of charge compensation is directly observed by capillary electrophoresis for a negatively charged peptide in aqueous solutions of trivalent cations. Atomistic and coarse-grained simulations provide molecular interpretation of this effect showing that it is
Chao Li et al.
Bioconjugate chemistry, 23(9), 1832-1837 (2012-08-09)
Genome manipulation controlled by small metal complexes has attracted extensive interest because of their potential application in the fields of molecular biotechnology and drug development. However, their medicinal application is still limited due to the distinct toxicity of the free
Nam Muk Oh et al.
Colloids and surfaces. B, Biointerfaces, 101, 298-306 (2012-09-27)
Advanced materials that have controllable pH-responsive properties when submerged in the lysosome have a great potential in intracellular drug delivery. We developed novel poly(L-amino acid) nanogels that were prepared by a facile cross-linking of poly[L-aspartic acid-g-(3-diethylaminopropyl)]-b-poly(ethylene glycol)-maleimide [poly(L-Asp-g-DEAP)-b-PEG-Mal] and poly(L-aspartic
Kyung Hyun Min et al.
Biomaterials, 33(23), 5788-5797 (2012-05-18)
A mineral (calcium phosphate, CaP)-reinforced core-shell-corona micelle was evaluated as a nanocarrier of doxorubicin (DOX) for cancer therapy. The polymer micelles of poly(ethylene glycol)-b-poly(L-aspartic acid)-b-poly(L-phenylalanine) (PEG-PAsp-PPhe) in the aqueous phase provided the three distinct functional domains: the hydrated PEG outer
Tomoya Suma et al.
Biomaterials, 33(9), 2770-2779 (2011-12-28)
The delivery of siRNA therapeutics owes its success to the development of carrier systems with high efficacy and minimum toxicity. Here, cationic polyaspartamide derivatives with a regulated number and spacing of positively charged amino groups in the side chain were
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