P2533

Poly-L-ornithine hydrochloride

suitable for ligand binding assays, Mol wt 15,000-30,000

• Synonym(s): L-Ornithine homopolymer hydrochloride
• CAS Number: 26982-21-8
• MDL number: MFCD00166412
• UNSPSC Code: 12352209
• PubChem Substance ID: 24898334
• NACRES: NA.26

Properties

• product name: Poly-L-ornithine hydrochloride, mol wt 15,000-30,000
• form: powder or solid
• mol wt: 15,000-30,000
• technique(s): ligand binding assay: suitable
• color: white to off-white
• storage temp.: −20°C
• SMILES string: Cl.NCCCC(N)C(O)=O

Description

Application

Poly-L-ornithine hydrochloride has been used as a substrate analog of acetyl-poly-L-lysine to study substrate binding and catalysis of the NAD-dependent protein deacetylase Hst2. It has been used to bind alginate-polycation-alginate (APA) microcapsules.

Biochem/physiol Actions

Poly-L-ornithine is a polycationic synthetic amino acid polymer. It boosts nasal absorption of hydrophilic macromolecular drugs. Poly-L-ornithine is a specialized coating that acts as a charge modifier.

Analysis Note

Molecular weight based on viscosity.

Other Notes

For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves