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biological source
human
form
liquid
growth mode
Adherent
karyotype
2n=46
morphology
elongated/polarized, neuronal
shipped in
dry ice
storage temp.
−196°C
Cell Line Description
Control line derived from the parental XCL-1, an integration-free iPSC line
Application
These products provide unique and versatile tools for the study of central nervous system (CNS) disorders, such as Alzheimer′s disease (AD), Parkinson′s disease (PD), autism, schizophrenia, and amyotrophic lateral sclerosis (ALS), as well as for drug screening and toxicology applications in the neural space.
Features and Benefits
This product contains cryo-preserved, pre-differentiated mixed population neurons derived from a footprint-free, karyotype normal human iPSC line. It was designed for customers to generate mature neurons using the optimized maturation medium and supplement (NEUR1050, NEUR1051 sold separately). Mature neurons can be obtained within 8 days. The neurons can be seeded on various culture vessel formats including 96 well plates on either glass or plastic surfaces and cultured as adherent cells. Shortly after seeding, the cells proliferate slightly for up to 3 days and show extensive neurite outgrowth and proper neuronal morphology. In general, at 8 days post-seeding, the cell population will contain ≥98% neurons and ≤1% Glial Fibrillary Acidic Protein (GFAP) positive astrocytes.
Culture Medium
User must also purchase Neuronal Maturation Medium, NEUR1050 (50mL) or NEUR1051 (250mL). Sold separately.
Subculture Routine
No subculture routine is necessary. See technical bulletin for additional details.
Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Lot/Batch Number
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