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M4252

Sigma-Aldrich

α-Methyl-DL-methionine

Synonym(s):

Methionine antagonist

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About This Item

Empirical Formula (Hill Notation):
C6H13NO2S
CAS Number:
Molecular Weight:
163.24
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:

Assay

≥98% (TLC)

form

powder

color

white

SMILES string

CSCCC(C)(N)C(O)=O

InChI

1S/C6H13NO2S/c1-6(7,5(8)9)3-4-10-2/h3-4,7H2,1-2H3,(H,8,9)

InChI key

ZYVMPHJZWXIFDQ-UHFFFAOYSA-N

Biochem/physiol Actions

α-Methyl-DL-methionine is a methionine antagonist.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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The in vivo metabolic pattern of low-grade brain gliomas: a positron emission tomographic study using f-18-fluorodeoxyglucose and c-11-L-methylmethionine.
T Hölzer
Neurosurgery, 42(5), 1200-1201 (1998-05-20)
An evaluation of four commercial HPLC chiral detectors: A comparison of three polarimeters and a circular dichroism detector
Kott, L. et al.
Journal of Pharmaceutical and Biomedical Analysis, 43, 53-65 (2007)
A I Magee
Current protocols in cell biology, Chapter 7, Unit 7-Unit 7 (2008-01-30)
This unit provides protocols for prenylation and carboxy-methylation of proteins in cultured cells. These modifications often accompany fatty acid acylation. Cultured cells can be labeled biosynthetically using radiolabeled mevalonate, a precursor, to label intermediates that are incorporated as prenoids--e.g., farnesyl
K Burgess et al.
Biopolymers, 42(4), 439-453 (1997-10-05)
A comparative study of four peptidomimetics of the sequence Phe-Met-Arg-Phe-amide (FMRFa) was performed to compare the conformational bias caused by trans-2,3-methanomethionine and alpha-methylmethionine stereoisomers. The specific compounds studied were {(2S,3S)-cyclo-M} RFa, F{(2R,3R)-cyclo-M} RFa, F{(S)-alpha-Mem} RFa, and F{(R)-alpha-MeM} RFa. Molecular simulations
Junfang Zhao et al.
Physical chemistry chemical physics : PCCP, 11(35), 7629-7639 (2009-12-03)
Methionine, alpha-methylmethionine and S-methylcysteine radical cations have been formed by oxidative dissociations of [CuII(M)(CH3CN)2]*2+ complexes. The radical cations M*+ were trapped, and CID spectra (MS3) of these ions are presented. Fragmentations of the methionine and S-methylcysteine radical cations, initiated by

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