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L4395

Sigma-Aldrich

Liposome Kit: Lipid mixtures for the preparation of liposomes

lyophilized powder

Synonym(s):

cholesterol, L-α-phosphatidylcholine and stearylamine kit

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About This Item

EC Number:
UNSPSC Code:
12352211
NACRES:
NA.25

biological source

egg yolk

Quality Level

form

lyophilized powder

composition

Cholesterol, 9 μmol/package
L-α-Phosphatidylcholine (egg yolk), 63 μmol/package
Stearylamine, 18 μmol/package

functional group

carboxylic acid

shipped in

ambient

storage temp.

−20°C

Related Categories

Application

Liposome Kit has been used for the preparation of liposomes.

Biochem/physiol Actions

Liposome Kit: Lipid mixtures for the preparation of liposomes contains cholesterol; L-α-phosphatidylcholine and stearylamine. Liposome kit may be used to prepare cationic (positively charge) liposomes for incorporation of materials into cells.
Liposomes can be used for different applications such as drug delivery, diagnostics, membrane models, adjuvants for vaccination and others. This lipid mixture can be used to encapsulate a broad spectrum of hydrophilic and amphipathic molecules of low, medium, and high molecular weight (including peptides, proteins, and oligo- and polynucleotides).

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Pictograms

CorrosionEnvironment

Signal Word

Danger

Hazard Statements

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Preparation and pharmacodynamic evaluation of liposomes of indomethacin.
Srinath P, Vyas SP, Diwan PV.
Drug Devel. Ind. Pharm., 26, 313-321 (2000)
Santosh Kumar et al.
JCI insight, 6(4) (2021-01-15)
Prime-boost immunization strategies are required to control the global tuberculosis (TB) pandemic, which claims approximately 3 lives every minute. Here, we have generated an immunogenic complex against Mycobacterium tuberculosis (M.tb), consisting of promiscuous T cell epitopes (M.tb peptides) and TLR
Xuan T A Nguyen et al.
Molecular neurobiology, 56(9), 6121-6133 (2019-02-08)
The cellular prion protein (PrPC), mainly known for its role in neurodegenerative diseases, is involved in several physiological processes including neuritogenesis. In addition, its ability to bind copper or zinc has been suggested for its role in metal homeostasis. Although
Abstracts of the Congress of the European Association of Nuclear Medicine. 25-29 August 2001, Napoli, Italy.
European journal of nuclear medicine, 28(8), 961-1298 (2001-09-06)
Giulietta Pinato et al.
Journal of biomedical optics, 16(9), 095001-095001 (2011-09-29)
Spatially confined and precise time delivery of neuroactive molecules is an important issue in neurophysiology. In this work we developed a technique for delivering chemical stimuli to cultured neurons consisting in encapsulating the molecules of interest in liposomes. These vectors

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