GW22790

Anti-TLR9 antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

• MDL number: MFCD03456046
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: chicken
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• species reactivity: rat, human, mouse
• manufacturer/tradename: Genway 15-288-22790
• technique(s): western blot: suitable
• NCBI accession no.: NP_059138.1
• UniProt accession no.: Q9NR96
• shipped in: wet ice
• storage temp.: −20°C
• Gene Information: human ... TLR9(54106)

Description

Immunogen

Immunogen Sequence: GI # 8394456, sequence 311-465

Recombinant toll-like receptor 9 isoform A

Application

Anti-TLR9 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Biochem/physiol Actions

Toll-like receptor 9 is a protein encoded by the TLR9 gene in humans. It is a cellular DNA-receptor and is widely expressed in breast as well as other cancers. It plays an important role in the pathogenesis of systemic lupus erythematosus (SLE) and has an impact on organ involvement in SLE. Expression of TLR-9 is a good indicator and helps in distinguishing cancer patients from benign and normal controls. TLR9 plays a crutial role in sensing a wide range of pathogens, including bacteria, fungi and viruses. Dysregulation of its signaling may contribute to a higher risk of developing cancers.

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide.

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves