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46943

Sigma-Aldrich

Fluorescein dilaurate

suitable for fluorescence, ≥97.0% (HPCE)

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About This Item

Empirical Formula (Hill Notation):
C44H56O7
CAS Number:
7308-90-9
Molecular Weight:
696.91
Beilstein:
6034843
EC Number:
230-764-2
MDL number:
MFCD00038409
UNSPSC Code:
12352106
PubChem Substance ID:
57650888
NACRES:
NA.32

Assay

≥97.0% (HPCE)

form

powder

solubility

ethanol: soluble

fluorescence

λex 490 nm; λem 514 nm in 0.1 M Tris pH 8.0 (esterase)

suitability

suitable for fluorescence

SMILES string

CCCCCCCCCCCC(=O)Oc1ccc2c(Oc3cc(OC(=O)CCCCCCCCCCC)ccc3C24OC(=O)c5ccccc45)c1

InChI

1S/C44H56O7/c1-3-5-7-9-11-13-15-17-19-25-41(45)48-33-27-29-37-39(31-33)50-40-32-34(49-42(46)26-20-18-16-14-12-10-8-6-4-2)28-30-38(40)44(37)36-24-22-21-23-35(36)43(47)51-44/h21-24,27-32H,3-20,25-26H2,1-2H3

InChI key

MYTRGBGGRICZGN-UHFFFAOYSA-N

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Application

Fluorescein dilaurate is suitable as fluorogenic substrate for esterases/lipases and used in the pancreolauryl test for chronic pancreatitis.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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F Seibold et al.
Journal of clinical gastroenterology, 22(3), 202-206 (1996-04-01)
Pancreatic autoantibodies (PABs) are found in 31% of patients with Crohn's disease (CD), but they do not correlate with the activity of intestinal disease or the incidence of acute pancreatitis. Exocrine pancreatic insufficiency has been observed in patients with CD.
E Małecka-Panas et al.
Polskie Archiwum Medycyny Wewnetrznej, 94(4), 315-323 (1995-10-01)
The aim of the presented study was a comparative evaluation of the three indirect pancreatic function tests: pancreolauryl-test (PLT), NBT-PABA test and faecal chymotrypsin (CH) efficacy in detecting pancreatic exocrine function impairment in advanced chronic pancreatitis (acp). 30 patients with
Z Wójcik et al.
Polski tygodnik lekarski (Warsaw, Poland : 1960), 50(1-35), 791-793 (1995-01-01)
Fifteen patients with chronic pancreatitis were qualified for surgical treatment on the basis of the results of endoscopic retrograde cholangiopancreatography, pancreolauryl test and glucose tolerance test. Significant changes according to Cambridge scale correlated with exocrine-endocrine pancreatic failure. In patients with
D A Elphick et al.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 5(2-3), 196-200 (2005-04-26)
The urine pancreolauryl ratio (uPLR) and, more recently, the faecal pancreatic elastase-1, are widely used for the noninvasive diagnosis of exocrine pancreatic insufficiency. Both tests have previously been validated against 'gold standard' tests of pancreatic function, but their use in
J Sarles
Annales de pediatrie, 39(4), 221-225 (1992-04-01)
The exocrine pancreas produces many of the enzymes responsible for the digestion of food. Severe alterations in exocrine pancreas function cause malabsorption which predominantly affects fats. Unfortunately, because it is a deep organ the pancreas is a difficult target for
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