Dextran is a polymer of anhydroglucose. It is composed of approximately 95% alpha-D-(166) linkages. The remaining (163) linkages account for the branching of dextran.
Application
Dextran sulfate (Sigma) can be used to precipitate the lipoprotein HDL from human plasma samples. [1]
Dextran sulfate is routinely used for the selective precipitation of lipoproteins, probe hybridization membrane-immobilized DNA, the release of DNA from DNA-histone complexes, and the inhibition of RNA binding to ribosomes.
Preparation Note
Sigma dextrans are derived from Leuconostoc mesenteroides.
Other Notes
To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.
Journal of lipid research, 42(8), 1308-1317 (2001-08-03)
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