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40165

Sigma-Aldrich

Dimethyldioctadecylammonium bromide

≥98.0% (AT)

Synonym(s):

Distearyldimethylammonium bromide

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About This Item

Linear Formula:
[CH3(CH2)17]2N(Br)(CH3)2
CAS Number:
Molecular Weight:
630.95
Beilstein:
3580323
EC Number:
MDL number:
UNSPSC Code:
12161900
PubChem Substance ID:
NACRES:
NA.25

description

cationic

Quality Level

Assay

≥98.0% (AT)

mol wt

630.95 g/mol

technique(s)

dialysis: suitable
enzyme immunoassay: suitable
protein purification: suitable

mp

~160 °C

SMILES string

CCCCCCCCCCCCCCCCCC[N+](CCCCCCCCCCCCCCCCCC)(C)C.[Br-]

InChI

1S/C38H80N.BrH/c1-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-35-37-39(3,4)38-36-34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-2;/h5-38H2,1-4H3;1H/q+1;/p-1

InChI key

PSLWZOIUBRXAQW-UHFFFAOYSA-M

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Eloi Feitosa et al.
PloS one, 7(9), e44702-e44702 (2012-09-13)
Dioctadecyldimethylammonium bromide (DODAB) is a double chain cationic lipid, which assembles as bilayer structures in aqueous solution. The precise structures formed depend on, e.g., lipid concentration and temperature. We here combine differential scanning calorimetry (DSC) and X-ray scattering (SAXS and
Agnes Michanek et al.
Langmuir : the ACS journal of surfaces and colloids, 28(25), 9621-9633 (2012-05-26)
The objective of this work is to establish under which conditions short RNA molecules (similar to miRNA) associate with zwitterionic phospholipids and how this differs from the association with cationic surfactants. We study how the base pairing (i.e., single stranded
Paolo Sabatino et al.
The journal of physical chemistry. B, 116(30), 9269-9276 (2012-06-27)
The interaction between phenol molecules, both in their undissociated and dissociated states, and cationic dioctadecyl dimethylammonium chloride (DODAC) vesicles were thoroughly investigated using NMR techniques. In particular, diffusion and relaxation measurements, combined with the two sites Kärger model, were used
Randip Kaur et al.
Journal of controlled release : official journal of the Controlled Release Society, 164(3), 331-337 (2012-07-18)
The mechanism behind the immunostimulatory effect of the cationic liposomal vaccine adjuvant dimethyldioctadecylammonium and trehalose 6,6'-dibehenate (DDA:TDB) has been linked to the ability of these cationic vesicles to promote a depot after administration, with the liposomal adjuvant and the antigen
Randip Kaur et al.
Journal of controlled release : official journal of the Controlled Release Society, 158(1), 72-77 (2011-10-29)
The adjuvant efficacy of cationic liposomes composed of dimethyldioctadecylammonium bromide and trehalose dibehenate (DDA:TDB) is well established. Whilst the mechanism behind its immunostimulatory action is not fully understood, the ability of the formulation to promote a 'depot effect' is a

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