Y0001805

Pregabalin

European Pharmacopoeia (EP) Reference Standard

• Synonym(s): (S)-3-(Aminomethyl)-5-methylhexanoic acid, CI-1008, PD-144723
• Empirical Formula (Hill Notation): C₈H₁₇NO₂
• CAS Number: 148553-50-8
• Molecular Weight: 159.23
• MDL number: MFCD00917044
• UNSPSC Code: 41116107
• PubChem Substance ID: 329831580
• NACRES: NA.24

Properties

• grade: pharmaceutical primary standard
• API family: pregabalin
• manufacturer/tradename: EDQM
• drug control: USDEA Schedule I
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C
• SMILES string: OC(C[C@@H](CN)CC(C)C)=O
• InChI: 1S/C8H17NO2/c1-6(2)3-7(5-9)4-8(10)11/h6-7H,3-5,9H2,1-2H3,(H,10,11)/t7-/m0/s1
• InChI key: AYXYPKUFHZROOJ-ZETCQYMHSA-N
• Gene Information: human ... CACNA1A(773) , CACNA1B(774) , CACNA1C(775) , CACNA1D(776) , CACNA1E(777) , CACNA1F(778) , CACNA1G(8913) , CACNA1H(8912) , CACNA1I(8911) , CACNA1S(779) , CACNA2D1(781) , CACNA2D2(9254) , CACNA2D3(55799) , CACNA2D4(93589) , CACNB1(782) , CACNB2(783) , CACNB3(784) , CACNB4(785) , CACNG1(786) , CACNG2(10369) , CACNG3(10368) , CACNG4(27092) , CACNG5(27091) , CACNG6(59285) , CACNG7(59284) , CACNG8(59283)

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including MSDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Pregabalin EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem/physiol Actions

Pregabalin is a lipophilic GABA analog/ligand at α2δ subunit of voltage-dependent Ca2+ channels. Pregabalin is an anticonvulsant, anxiolytic analgesic used to treat peripheral neuropathic pain and fibromyalgia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Safety Information

• Pictograms: GHS08,GHS07
• Signal Word: Warning
• Hazard Statements: H336,H361
• Precautionary Statements: P201 - P202 - P261 - P271 - P280 - P308 + P313
• Hazard Classifications: Repr. 2 - STOT SE 3
• Target Organs: Central nervous system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable