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H9645

Supelco

p-Hydroxymethamphetamine

analytical standard, for drug analysis

Synonym(s):

Pholderin

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About This Item

Empirical Formula (Hill Notation):
C10H15NO
CAS Number:
370-14-9
Molecular Weight:
165.23
EC Number:
206-725-0
MDL number:
MFCD00178702
UNSPSC Code:
41116107
PubChem Substance ID:
329815268
NACRES:
NA.24

grade

analytical standard, for drug analysis

Quality Level

200

Assay

≥98% (TLC)

drug control

Home Office Schedule 1; regulated under CDSA - not available from Sigma-Aldrich Canada

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

storage temp.

−20°C

SMILES string

CNC(C)Cc1ccc(O)cc1

InChI

1S/C10H15NO/c1-8(11-2)7-9-3-5-10(12)6-4-9/h3-6,8,11-12H,7H2,1-2H3

InChI key

SBUQZKJEOOQSBV-UHFFFAOYSA-N

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

A metabolite of methamphetamine; sympathomimetic

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
13100905
037M4150V
016M4036V
095M4039V

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T Yamamoto et al.
Journal of analytical toxicology, 13(2), 117-119 (1989-03-01)
A sensitive and specific gas chromatography/mass spectrometry (GC/MS) method has been developed for the simultaneous analysis of methampthetamine and its metabolites (amphetamine, p-hydroxymethamphetamine, and p-hydroxyamphetamine) in monkey urine. The method has been applied to the analysis of urine samples from
Shimosato, K., et al.
Journal of Chromatographic Science, 377, 279-279 (1986)
H Wilhelm et al.
Klinische Monatsblatter fur Augenheilkunde, 204(3), 169-175 (1994-03-01)
Pharmacologic testing by indirect acting sympathomimetics like hydroxyamphetamine may determine the site of the lesion in Horner's syndrome. Pholedrine is chemically similar to hydroxyamphetamine. Therefore we examined if it shows the same effects in normal subjects and in patients with
Noriaki Shima et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 830(1), 64-70 (2005-11-03)
Two conjugates of p-hydroxymethamphetamine (p-OHMA), p-OHMA-glucuronide (p-OHMA-Glu) and p-OHMA-sulfate (p-OHMA-Sul) have been identified in methamphetamine (MA) users' urine by using liquid chromatography-high resolution tandem mass spectrometry (LC-HRMS-MS). The synthesis of p-OHMA-Glu and p-OHMA-Sul, and an LC-MS procedure for the simultaneous
Manfred T Birchler et al.
The Annals of otology, rhinology, and laryngology, 111(12 Pt 1), 1087-1091 (2002-12-25)
We report the case of a 17-year-old man who presented with left-sided Horner's syndrome. Magnetic resonance imaging revealed a spindle-shaped cervical tumor in the left paravertebral space. During operation, a tumor originating from the left sympathetic trunk was found. The
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