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Ethoxyquin

PESTANAL®, analytical standard

Synonym(s):

1,2-Dihydro-6-ethoxy-2,2,4-trimethylquinoline, 6-Ethoxy-1,2-dihydro-2,2,4-trimethylquinoline

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About This Item

Empirical Formula (Hill Notation):
C14H19NO
CAS Number:
Molecular Weight:
217.31
Beilstein:
158223
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
E Number:
E324
NACRES:
NA.24

grade

analytical standard

Quality Level

product line

PESTANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

density

1.03 g/mL at 20 °C (lit.)

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

neat

shipped in

wet ice

storage temp.

2-8°C

SMILES string

CCOc1ccc2NC(C)(C)C=C(C)c2c1

InChI

1S/C14H19NO/c1-5-16-11-6-7-13-12(8-11)10(2)9-14(3,4)15-13/h6-9,15H,5H2,1-4H3

InChI key

DECIPOUIJURFOJ-UHFFFAOYSA-N

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General description

Ethoxyquin (EQ), an aromatic compound, is an antioxidant mostly used in animal and fish feeds. It is seen to inhibit carcinogenic effects of polycyclic aromatic hydrocarbons. Oxidation initiated by air, light or transition metals in unsaturated lipids can be stopped from propagation by EQ.

Application

EQ has been used as external standard in the determination of EQ and its major metabolite from Atlantic salmon tissues using HPLC with fluorescence detector.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Caution

Light sensitive: sensitive
Air sensitive: Handle under argon

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

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Laia Sanchez Costa et al.
Analytical methods : advancing methods and applications, 12(32), 4080-4088 (2020-08-08)
Ethoxyquin (EQ) is a quinolone commonly used as an antioxidant additive and a fungicide. However, Regulation (EU) 2017/962 suspended its authorisation as a feed additive for all animal species and categories. The aim of this study is thus to ensure
The inhibitory effects of ethoxyquin on the carcinogenic action of aflatoxin B1 in rats.
Cabral JR, Neal GE.
Cancer Letters, 19(2), 125-132 (1983)
Alina Błaszczyk et al.
Acta poloniae pharmaceutica, 62(2), 111-115 (2005-09-16)
In our study ethoxyquin (EQ) and its two complexes with flavonoids were obtained from ethoxyquin (1,2-dihydro-6-ethoxy-2,2,4-trimethylquinoline, EQ) and quercetin (EQ-Q, 1:1) or rutin (EQ-R, 1:1). Cytotoxicity of the tested compounds was studied using the trypan blue exclusion method and the
Alina Błaszczyk
Toxicology letters, 163(1), 77-83 (2005-11-04)
Ethoxyquin (1,2-dihydro-6-ethoxy-2,2,4-trimethylquinoline, EQ) is widely used in various food products and in animal feeds because of its powerful antioxidant activity. This compound was recently found to cause not only many unfavourable side-effects in animals fed with feeds containing it, but
Alina Błaszczyk et al.
Chemico-biological interactions, 162(3), 268-273 (2006-09-09)
Four newly synthesized salts of ethoxyquin (EQ: 1,2-dihydro-6-ethoxy-2,2,4-trimethylquinoline), an antioxidant used in animal feeds, were evaluated with the use of the comet assay performed on human lymphocytes: ethoxyquin ascorbate, ethoxyquin hexanoate, ethoxyquin salicylate and ethoxyquin salt of Trolox C (6-hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic

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