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09656

Sigma-Aldrich

1-Hydroxybenzotriazole polymer-bound

100-300 mesh, extent of labeling: ~1.0 mmol/g loading, matrix polystyrene, crosslinked with 2% DVB

Synonym(s):

1-Hydroxybenzotriazole-6-carboxamide bound to polystyrene crosslinked with DVB, HOBt polymer-bound

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About This Item

MDL number:
MFCD01635667
UNSPSC Code:
12352200
PubChem Substance ID:
329748786
NACRES:
NA.22

reaction suitability

reaction type: solution phase peptide synthesis

Quality Level

100

extent of labeling

~1.0 mmol/g loading

matrix

polystyrene, crosslinked with 2% DVB

particle size

100-300 mesh

Other Notes

Polymer bound HOBt for the synthesis of amides and peptides with carbodiimides and other activating reagent without racemization

Pictograms

Flame
GHS02

Signal Word

Danger

Hazard Statements

H228

Precautionary Statements

P210

Hazard Classifications

Flam. Sol. 1

Storage Class Code

4.1B - Flammable solid hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0001402925
016922/1V
1402925V
016922/1
1402925

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K. Dendrinos et al.
Chemical Communications (Cambridge, England), 499-499 (1998)
Iuliana E. Pop et al.
The Journal of organic chemistry, 62(8), 2594-2603 (1997-04-18)
The synthesis of a new polymer-supported coupling reagent derived from 1-hydroxybenzotriazole is described. An aminomethylated polystyrene was functionalized by reaction with 3-nitro-4-chlorobenzenesulfonyl chloride (2) followed by treatement with hydrazine hydrate, to give the polymeric N-benzyl-1-hydroxybenzotriazole-6-sulfonamide (4).The polymeric reagent 4 was

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