03334

Dansylhydrazine

for LC-MS derivatization, LiChropur^™, ≥95% (HPLC)

• Synonym(s): 5-(Dimethylamino)-1-naphthalenesulfonic hydrazide, 5-(Dimethylamino)naphthalene-1-sulfono­hydra­zide, Dns-Hz
• Linear Formula: (CH₃)₂NC₁₀H₆SO₂NHNH₂
• CAS Number: 33008-06-9
• Molecular Weight: 265.33
• Beilstein: 2868662
• EC Number: 251-337-7
• MDL number: MFCD00003986
• UNSPSC Code: 41116105
• PubChem Substance ID: 329747590
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: ≥95% (HPLC)
• quality: LiChropur^™
• technique(s): LC/MS: suitable
• mp: 126-130 °C (lit.)
• suitability: conforms to structure for Infrared spectrum
• SMILES string: CN(C)c1cccc2c(cccc12)S(=O)(=O)NN
• InChI: 1S/C12H15N3O2S/c1-15(2)11-7-3-6-10-9(11)5-4-8-12(10)18(16,17)14-13/h3-8,14H,13H2,1-2H3
• InChI key: KPQYDVAFRDWIBW-UHFFFAOYSA-N

Description

General description

Dansylhydrazine (DNSH) is a fluorescent reagent which is commonly utilized for derivatization of carbonyl compounds.

Application

Suitable for LC-MS derivatization.
DNSH has been used for the analytical derivatization of malondialdehyde prior to its determination in human plasma by liquid chromatography-mass spectrometry (LC-MS).
It may be used as a derivatization agent for thujone prior to its determination in white Italian vermouth samples by reversed phase LC with fluorescence detection combined with tandem MS and as a fluorescent label for the quantification of neuroactive steroids, alphaxalone and pregnanolone in plasma by isocratic reversed-phase high-performance liquid chromatography (RP-HPLC).

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Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable