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MATRNPS50

Millipore

96 well Collection Plate

Clear, Non-Sterile, Transport Receiver Plate, 100uL volume, 50 plates, Styrene

Synonym(s):

96-well plate, Microplate

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About This Item

UNSPSC Code:
41104923
eCl@ss:
32039006
NACRES:
NB.22

material

polystyrene

Quality Level

sterility

non-sterile

product line

MultiScreen®

manufacturer/tradename

MultiScreen®

parameter

100 μL sample volume (per well)

technique(s)

cell culture | mammalian: suitable
parallel artificial membrane permeation assay (PAMPA): suitable

plate size

96 wells

shipped in

ambient

General description

MultiScreen-Mesh plate with receiver plate provides a complete system for culturing, testing and reading assay results in a one-step protocol. This system is ideal for target screening and other applications that evaluate new compounds using multicellular organisms as the in vivo model.

MultiScreen-Mesh is optimized for compound and target identification in a 96-well format. The 96-well nylon mesh plate and 96-well tray fit together to provide a ready-to-use system for assays measuring paralysis, cytotoxicity, and death of multicellular organisms. Select from a range of mesh pore sizes to appropriate for your application. Simply transfer parasites, nematodes or other multicellular organisms into the wells, treat with target compound, and measure the migration of the organisms. The plates are optically clear for use with an imaging microscope or other microscopic analysis. Plates can be coated with a thin layer of agar if necessary.

MultiScreen-Mesh plates have also been shown to be useful as high throughput cell strainers prior to cellular analysis in a FACS analyzer. To dissociate clumps of cells prior to loading plate into FACS instrument, run cell suspensions through the mesh plates either by gravity flow or via gentle centrifugation.

This filter plate provides a complete system for culturing, testing and reading assay results in a one-step protocol. The system is ideal for target screening and other applications that evaluate the effect of new compounds on whole, multicellular organisms. The MultiScreen-Mesh filter plate is optimized for compound and target identification in a 96-well format. The filter plate and 96-well tray fit together to provide a ready-to-use system for assays measuring paralysis, cytotoxicity, and death of multicellular organisms. Simply transfer parasites, nematodes or other multicellular organisms into the wells, treat with target compound, and measure the migration of the organisms.

Features & Benefits:
- Multiple configurations and applications
- Chemical compatibility
- Automation-compatible
- Superior vacuum filtration and filtrate collection
- Plates are optically clear for use with an imaging microscope or other microscopic analysis

Applications
- Whole Organism Screening

Application

Research Category
Cell Culture

Protein

Physical form

Color Code: Clear

Other Notes

Automation Compatible: No

Legal Information

MULTISCREEN is a registered trademark of Merck KGaA, Darmstadt, Germany

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Articles

This is a white paper on the Evaluation of the reproducibility of Parallel Artificial Membrane Permeation Assays (PAMPA) using MultiScreen® Filter Plates.

This is a protocol for a Membrane Integrity test for Lipid-PAMPA Artificial Membranes

Combining solubility & PAMPA assays streamlines drug permeability testing.

Protocols

Assays that predict passive absorption of orally administered drugs have become increasingly important in the drug discovery process. As previously described by Faller and Kansy such assays provide rapid, low cost and automation friendly methods to measure a compound’s passive permeability.

The ELISpot (Enzyme Linked Immuno-Spot) assay provides an effective method of measuring the antibody or cytokine production of immune cells on the single cell level.

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