MAB354
Anti-Somatostatin Antibody, clone YC7
culture supernatant, clone YC7, Chemicon®
Synonym(s):
Anti-Somatostatin
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All Photos(5)
About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Recommended Products
biological source
rat
Quality Level
antibody form
culture supernatant
antibody product type
primary antibodies
clone
YC7, monoclonal
species reactivity
rabbit, rat, human
manufacturer/tradename
Chemicon®
technique(s)
immunohistochemistry: suitable
isotype
IgG2b
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... SST(6750)
General description
Somatostatin (also known as growth hormone inhibiting hormone (GHIH) or somatotropin release-inhibiting factor (SRIF) has two active forms, 14 amino acids and 28 amino acids, which are produced by alternate cleavage of the single preproprotein. Somatostatin is expressed widely and acts to inhibit the release of several secondary hormones by binding to high-affinity G-protein coupled somatostatin receptors. Presence of somatostatin has been shown in sympathetic nerves, mucosal cells, myenteric nerves of the gastrointestinal tract, salivary glands and in some parafollicular cells of the thyroid.
Specificity
Anti-SST, clone YC7 recognizes Somatostatin. Shows no cross-reactivity to enkephalins, other endorphins, substance P or CGRP. Partially cross-reacts with somatostatin fragments.
Immunogen
Synthetic peptide corresponding to amino acids 1-14 of cyclic somatostatin conjugated to bovine thyroglobulin using carbodiimide.
Application
Anti-Somatostatin Antibody, clone YC7 is an antibody against Somatostatin for use in IH.
Immunohistochemistry at 1:50-1:100 on human brain.
Optimal working dilutions must be determined by the end user.
Optimal working dilutions must be determined by the end user.
Physical form
Lyophilized Supernatant, preservative free.
Storage and Stability
Lyophilized antibody can be kept at 2-8°C for up to 3 months and should be kept at -20°C for long term storage. Reconstitute with 100μL sterile DI water. Maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.
Analysis Note
Control
Pancreas, Brain
Pancreas, Brain
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Recruitment of Perisomatic Inhibition during Spontaneous Hippocampal Activity In Vitro.
Beyeler, A; Retailleau, A; Molter, C; Mehidi, A; Szabadics, J; Leinekugel, X
Testing null
Cell type-specific inhibitory inputs to dendritic and somatic compartments of parvalbumin-expressing neocortical interneuron.
Hioki, H; Okamoto, S; Konno, M; Kameda, H; Sohn, J; Kuramoto, E; Fujiyama, F; Kaneko, T
The Journal of Neuroscience null
Function of dendritic spines on hippocampal inhibitory neurons.
Scheuss, V; Bonhoeffer, T
Cerebral Cortex (1991)
Frequency-invariant temporal ordering of interneuronal discharges during hippocampal oscillations in awake mice.
Varga, C; Golshani, P; Soltesz, I
Proceedings of the National Academy of Sciences of the USA null
Csaba Varga et al.
Cerebral cortex (New York, N.Y. : 1991), 25(11), 4430-4449 (2015-03-20)
Transcription factors contribute to the differentiation of cortical neurons, orchestrate specific interneuronal circuits, and define synaptic relationships. We have investigated neurons expressing chicken ovalbumin upstream promoter transcription factor II (COUP-TFII), which plays a role in the migration of GABAergic neurons.
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