The CHEMICON Cell Invasion Assay Kit is ideal for evaluation of invasive tumor cells. Each CHEMICON Cell Invasion Assay Kit contains sufficient reagents for the evaluation of 24 samples. The quantitative nature of this assay is especially useful for screening of pharmacological agents.
The CHEMICON Cell Invasion Assay Kit is intended for research use only; not for diagnostic or therapeutic applications.
Packaging
24 wells
Components
Sterile 24-well Cell Invasion Plate Assembly: (Part No. 90248) Two 24-well plates with 12 collagen-coated inserts per plate (24 inserts total/kit).
Cell Stain: (Part No. 90144) One 20 mL bottle.
Extraction Buffer: (Part No. 90145) One 20 mL bottle.
Cotton Swabs: (Part No. 10202) 50 each.
Forceps: (Part No. 10203) One each.
Storage and Stability
Store kit materials at 2-8°C for up to their expiration date. Do not freeze.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Breast cancer is the leading cause of cancer-associated death among women worldwide. Targeting breast cancer cell metastasis is an important therapeutic approach. The MAPK pathway is a key cell signaling pathway that plays a pivotal role in cellular invasion and
Use of a reconstituted basement membrane to measure cell invasiveness and select for highly invasive tumor cells.
Terranova, V P, et al.
Proceedings of the National Academy of Sciences of the USA, 83, 465-469 (1986)
A new in vitro assay for quantitating tumor cell invasion.
Repesh, L A
Invasion & Metastasis, 9, 192-208 (1989)
Tumor invasion and metastases: role of the basement membrane. Warner-Lambert Parke-Davis Award lecture.
L A Liotta
The American journal of pathology, 117(3), 339-348 (1984-12-01)
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