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Sigma-Aldrich

Src Substrate Peptide

Src Substrate Peptide primarily used in Kinase Assays.

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About This Item

UNSPSC Code:
12352202
eCl@ss:
32160405
NACRES:
NA.41

Quality Level

mol wt

Mw 1670 Da (1.67 kDa)

manufacturer/tradename

Upstate®

technique(s)

activity assay: suitable (kinase)

NCBI accession no.

UniProt accession no.

shipped in

wet ice

Gene Information

human ... SRC(6714)

General description

Synthetic peptide (KVEKIGEGTYGVVYK) corresponding to amino acids 6-20 of p34cdc2.

Biochem/physiol Actions

Protein Target: Src
Target Sub-Family: TK

Quality

Routinely evaluated in a protein kinase assay as a substrate for Src (p60c-src), (14-117) or Lck (p56lck), active (14-379).

Physical form

Lyophilized powder

Storage and Stability

Stable for 2 years at -20°C

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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B Y Chang et al.
Molecular and cellular biology, 18(6), 3245-3256 (1998-06-20)
To isolate and characterize proteins that interact with the unique domain and SH3 and SH2 domains of Src and potentially regulate Src activity, we used the yeast two-hybrid assay to screen a human lung fibroblast cDNA library. We identified RACK1
Kei Sakamoto et al.
The Journal of biological chemistry, 277(14), 11910-11917 (2002-01-26)
The protein serine/threonine kinase Akt/protein kinase B has been recognized as a critical signaling mediator for multiple cell systems. The function of Akt in skeletal muscle is not well understood, and whether contractile activity stimulates Akt activity has been controversial.
C K Szekeres et al.
The Journal of biological chemistry, 275(49), 38831-38841 (2000-08-23)
12(S)-Hydroxyeicosatetraenoic acid (12(S)-HETE), a 12-lipoxygenase metabolite of arachidonic acid, has multiple effects on tumor and endothelial cells, including stimulation of invasion and angiogenesis. However, the signaling mechanisms controlling these physiological processes are poorly understood. In a human epidermoid carcinoma cell

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